Respiration Flashcards
Where does aerobic respiration occur?
In the cytoplasm & mitochondria
Where does anaerobic respiration occur?
Only in the cytoplasm
What are the 4 steps of aerobic respiration?
Glycolysis
Link reaction
Kreb’s cycle
Oxidative phosphorylation
What is glycolysis?
Process by which a glucose molecule is converted to 2 molecules of pyruvate
Occurs in both aerobic and anaerobic respiration
What is the first step of glycolysis?
- 2 phosphate molecules are added to produce hexose bisphosphate
- glucose phosphorylation makes glucose more reactive so it can be split more easily
- phosphate molecules are taken from 2 hydrolysed ATP molecules
What is the second step of glycolysis?
Hexose bisphosphate is split to produce 2 triose phosphate molecules
What is the third step of glycolysis?
- dehydrogenase removes a hydrogen atom from each of the triose phosphate molecules
- oxidation + each H atom is accepted by an NAD+ molecule to produce NADH
- phosphates from each triose phosphate molecule are used to produce 2 ATP molecules each
What is the final result of glycolysis?
2 pyruvate molecules
2 NADH+ molecules
Net of 2 ATP
How does pyruvate get into the mitochondrial matrix?
It’s actively transported across by pyruvate H+ symport
What is the link reaction?
The conversion of 2 pyruvates to two 2-carbon acetyl groups through decarboxylation and dehydrogenation
What is the link reaction catalysed by?
Pyruvate dehydrogenase
What is the process of the link reaction?
- a carboxyl group is removed producing CO2
- Hydrogen atoms are removed from pyruvate and are accepted by NAD+ to form NADH
- acetyl group combines with coenzyme A to produce acetylCoA
What is the Krebs cycle?
A series of enzyme catalysed reactions that occur to oxidise the acetylCoA produced in the links reaction
For every glucose molecule there are 2 turns of the Krebs cycle
What is the first step of the Krebs cycle?
Acetyl group is release from acetylCoA
What is the second step of the Krebs cycle?
2C acetyl group combines with 4C oxaloacetate to form the 6C compound citrate