Control Of Blood-Glucose Levels Flashcards
What is insulin?
- hormone released from beta cells in the pancreas when blood glucose concentration rises
- travels in the blood + attaches to receptors on the surfaces of almost all cells
- brings about changes inside the cell that lower the glucose concentration in the blood
- stops being release after blood-glucose concentration has been lowered
What is insulin an example of?
Negative feedback
When is glycogenesis used?
When blood-glucose concentration is too high
When is glycogenolysis used?
When blood-glucose concentration is too low
When is gluconeogenesis used?
When blood glucose concentration is too low
Why can insulin not enter the cells?
Because it’s a peptide hormone
What happens when insulin binds to the insulin receptor?
- glucose transporter vesicles fuse with the cell surface membrane
- causes these vesicles to change shape so they let more glucose into the cell
- activates tyrosine kinase
Why is tyrosine kinase used?
- phosphorylates other enzymes to turn them from inactive to active which go on to reduce the blood glucose concentration
What is glucose converted into?
Fat & glycogen
What happens in glycogenesis?
Liver cell produce enzymes that convert glucose to glycogen which is stored in the liver cells
What happens in glycogenolysis?
The liver produces enzymes that break down the glycogen stored in the cells to glucose
What happens in gluconeogenesis?
The liver cells form glucose from glycerol and amino acids