Respi Physio Flashcards

1
Q

Conducting zone

A

Nose to terminal bronchioles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Air from nose to terminal bronchioles that does not undergo gas exchange

A

Anatomic dead space

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Normal anatomic dead space

A

150 ml

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Air in the respiratory unit of the lung that doesn’t undergo gas exchange

A

Alveolar dead space

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Normal alveolar dead space

A

0 ml

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Physiologic dead space is equal to

A

Anatomic + alveolar dead space

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Functional anatomic unit of the lung

A

Bronchopulmonary segments

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Respiratory unit of the lung

A

Respiratory bronchioles
Alveolar ducts
Alveolar sacs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Cell that Produces mucus for lubrication

A

Goblet cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Cell that Produces protective GAGs and metabolize airborne toxins

A

Clara cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Alveolar macrophages are also called

A

Dust cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Formula for physiologic dead space

A

TV x Paco2- Peco2
————–
Paco2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Alveolar ventilation formula

A

(TV-PDS) x RR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Air inspired over and above the tidal volume

A

Inspiratory reserve volume

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Lung volume used during exercise

A

Inspiratory reserve volume

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Amount of air inhaled or exhaled during the relaxed state

A

Tidal volume

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Normal tidal volume

A

500 ml

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Amount of air exhaled after expiration of tidal volume

A

Expiratory reserve volume

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Remaining air in the lungs after maximal exhalation

A

Residual volume

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Lung volumes cannot be measured by spirometry

A

RV
FRC
TLC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Maintains oxygenation in between breaths

A

RV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Equilibrium/ resting volume of the lung

A

FRC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Marker for lung function

A

FRC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Maximum volume of air that can be inhaled or exhaled

A

VC or FVC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Which volume remains in the lungs after a tidal volume is expired?
FRC
26
Which volume remains in the lungs after a maximal expiration?
RV
27
In a maximal expiration, the total volume expired is
VC
28
In obstructive lung disease, the FEV/FVC ratio is:
Decreased
29
In restrictive lung disease, the FEV/FVC ratio is
Normal or increased
30
Force caused by water molecules at the air liquid interface that tends to minimize surface area
Surface tension
31
Cells that produce surfactant
Type 2 pneumocyted
32
Active component of surfactant
DPPC | Dipalmitoylphosphatidylcholine
33
Main component of surfactant
Water
34
Test for surfactant
Amniotic L:S Ratio
35
Effect of surfactant on lung compliance
Increased
36
Major site of airway resistance
Medium sized bronchi
37
Driving force for diffusion
Partial pressure difference
38
Maximum amount of O2 that can bind to hemoglobin
O2 binding capacity
39
Normal O2 binding capacity
1.34
40
O2 -hemoglobin dissociation curve is ______ in shape
Sigmoidal
41
O2 dissociation curve shifts to the right when: CABET
``` Increased: CO2 Acidosis BPG Exercise Temperature ```
42
Decreased PaO2 but increased A-a gradient:
``` Diffusion defect (fibrosis) V/Q defect Right to left shunt ```
43
Pulmonary blood flow when supine
Same through entire lung
44
Pulmonary blood flow during standing
Lowest at apex highest at base
45
Causes of pulmonary global hypoxic vasoconstriction
High altitude | Fetal circulation
46
Leukotrienes causes
Bronchoconstriction
47
In which vascular bed does hypoxia cause vasoconstriction?
Pulmonary
48
Pulmonary circulation has _____ resistance compared to systemic
Lower
49
Normal V/Q ratio
0.8
50
V/Q is equal to zero
Shunt
51
V/Q is infinite
Dead space
52
High V/Q- high PO2 low PCO2 is found in
Lung apex
53
Part of the brain that created the basic respiratory rhythm
Medulla
54
Modifies the basic respiratory rhythm
Pons
55
Contains the apneustic and pneumotaxic centers
Pons
56
Main respiratory center
DRG
57
Control center for normal/resting inspiration
DRG
58
Control center for forced inspiration and expiration
VRG
59
Control center that shortens time for inspiration-- increased RR
Pneumotaxic center
60
Prolongs time for inspiration
Apneustic center
61
Central chemoreceptors are located in
Ventral Medulla
62
Central chemoreceptors respond to
CSF H levels
63
Peripheral chemoreceptors are found in
Carotid and aortic bodies
64
Peripheral chemoreceptors respond to
PaO2 <60mmHg
65
Mechanoreceptors that initiates the Hering Breuer reflex
Lung stretch receptors
66
Mechanoreceptors found in the juxtacapillary areas and is stimulated by pulmonary capillary engorgement
J receptors
67
Stimulation of J receptors causes
Rapid shallow breathing | Feeling of dyspnea
68
Arterial pH during strenuous exercise: increased or decreased?
Decreased
69
Arterial pH during moderate exercise: increased or decreased?
No change
70
Decreased respiratory response to high altitude
Alveolar PO2 | Arterial PO2