Respi Drugs Flashcards
More effective respi drug (and less toxic than beta agonist) in patients with COPD
Ipratropium
MOA of theophylline
PDE inhibitor
Adenosine receptor antagonist
Drug class of theophylline
Methylxanthine
Methylxanthine used for intermittent claudication
Pentoxifylline
Antidote for theophylline overdose
Beta blocker
Class of cromolyn
Mast cell stabilizer
Moa of cromolyn
Prevents calcium influx and stabilizes mast cells, preventing degranulation and release of histamine, leukotrienes and other mediators
Main SE of cromolyn
Airway irritation (often confused with an asthma attack)
Main SE of fluticasone
Oropharyngeal candidiasis
Lowest systemic steroid toxicity
Ciclesonide
Inhibitor of 5-lipoxygenase
Zileuton
SE of zileuton
Hepatitis
Elevated LFTs
Flulike sx
Montelukast blocks receptors for leukotrienes
C4 D4 E4
Montelukast can cause which rare syndrome
Churg strauss
Anti IgE antibody
Omalizumab