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Resp 3 Flashcards

1
Q

MET meaning

A

Metabolic equivalent of Task

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2
Q

1 MET =

A

3.5 mL/kg/min

240ml/min

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3
Q

At max exercise

Tidal Volume =

A

0.5 x Vital Capacity

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4
Q

Owles Point

A

Critical point of oxygen consumption where ventilation increases more in proportion to oxygen consumption

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5
Q

During ascending, inspired PIO2 is what compared to atmosphere?

A

less

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6
Q

3x acute responses from altitude

A

Hyperventilation

Alkalosis

Diuresis

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7
Q

What happens to 2,3 DPG during acclimatisation

A

Reduces

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8
Q

what mixture of gas is used in diving

A

Helium / Oxygen

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9
Q

Minute Ventilation equation

A

Breathing Frequency x Tidal Volume

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10
Q

What does the respiratory centre consist of (2)

What controls what?

A

Medulla + Pons

Pons regulates the Medulla

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11
Q

Positive Stimulation of the medulla (2)

A

Peripheral Chemoreceptors

Central Chemoreceptors

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12
Q

Peripheral Chemoreceptors stimulated by (3)

A

O2 decreasing

CO2 rising

H+ rising

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13
Q

Central Chemoreceptors stimulated by (2)

A

CO2 increasing

H+ rising

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14
Q

Baroreceptors does what to ventilation

A

Increases BP = decrease Ventilation

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15
Q

J receptors are activated when?

What does it do to ventilation?

A

Activated in Traumas

Increases

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16
Q

What leads to negative stimulation of the medulla/pons? (2)

A

Stretch receptors in lungs

irritant receptors in lungs

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17
Q

Negative stimulation is regulated by what nerve

A

Vagus nerve

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18
Q

Carotid / Aortic Bodies are sensitive to what (3)

A

Low O2

High CO2

High H+

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19
Q

Definition of Oxygen Delivery

A

O2 leaving heart in 1 min

20
Q

Definition of Oxygen Consumption

A

O2 used by body in 1 min

21
Q

Equation of Oxygen Delivery

A

O2 in blood x Cardiac Output

22
Q

Factors affecting oxygen consumption (3)

A

Age

temperature

Exercise

23
Q

Respiratory Exchange ratio

A

Ratio of CO2 production to O2 consumption

24
Q

Affected by respiratory exchange ratio (2)

A

Hyperventilation

Metabolic Fuel

25
Q

Antitussives

A

Cough Suppressants

26
Q

2 types of suppresants that affects afferent nerves which are cough suppresants

A

Linctuses

Steam

27
Q

Linctuses work where

A

above larynx

28
Q

antitussives work on what?

name 3 types

A

Medullary cough centre

Opiods // Non opiods // sedatives

29
Q

Expectorants increase what?

A

Volume of secretion

30
Q

Mucolytics decrease what?

A

Viscosity of secretion

31
Q

Prednisone is what?

A

Oral Corticosteroid

32
Q

Ciclesonide is what

A

Glucocorticoid

33
Q

Cromolyn sodium + Nedocromil Sodium

A

Inhibit MC (eosinophils)

34
Q

Prodrugs are what

A

Drugs that are biologically inactive unless placed in body

35
Q

Arachidonic acid —> Leukotriene

what enzyme

A

5 Lipoxygenase

36
Q

Motelukast + Zafirlukast are what

A

Leukotriene Receptor Antagonists

37
Q

Salbutamol + salmeterol work on what receptors

A

B2 Adrenoreceptors

38
Q

Theophylline + aminophylline increase what?

what drugs are they

A

increase bronchodilation

Methylxanthines

39
Q

Ipratropium + Tiotropium are what type of drug

What do they inhibit

A

Antichilinergic agents

Inhibits M3 receptors

40
Q

Omalizumab does what

A

inhibit IgE to MC

41
Q

Ketotifen does what

A

histamine receptor antagonist

42
Q

Magnesium sulphate causes what

A

Bronchodilation

43
Q

ketamine causes what

A

bronchodilation

44
Q

methylxanthines do what

A

Directly bronchodilate

45
Q

Sympathomimetics work how

A

mimic dilator neurotransmitters

46
Q

Antichilinergics do what

A

block constrictor transmitter

Body Systems (9 decks)

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