⭐ • Research Methods: Brain Scanning Flashcards
What are the 4 types of brain scanning techniques?
- MRI scan
- fMRI scan
- PET scan
- CAT/ CT scan
What does ‘CAT’/ CT stand for?
Computer
Assisted
Tomography
Scan
Describe the process of a CAT/ CT scan
- Removal of metals as will disrupt scan
- Lie on scanner table and keep still for entire 30 min procedure
- Series of X-ray beams passed through head via rotating
- Creates cross-sectional images of brain
- MAY require injection of dye to make blood vessels more clear
What are CAT/ CT scans used for?
- Looking for lesions/ structural damage or imperfections
- Looking for tumours
What are the advantages to a CAT/ CT scan?
- Painless, noninvasive, and accurate.
- Images bone, soft tissue, and blood vessels all at the same time
- Provides very detailed structural imaging
What are the disadvantages to a CAT/ CT scan?
- Radiation exposure due to x-ray beams - exposure to ionizing radiation
- Possible reactions to the contrast agent/ dye
What does ‘PET’ stand for?
Positron
Emission
Tomography
Scan
Describe the process of a PET scan
- Radioactive tracer injected
- Oxygen & glucose accumulate in brain areas that are metabolically active
- As glucosed used radioactive tracer breaks down releasing** neutron & positron**
- Upon positron hitting electron both are destryed and 2 gamma rays are released
- Gamma ray detectors record areas in which rays are emitted & image produced of activity
What to the colours represent in terms of brain activity in a PET scan?
- RED/YELLOW = high activity/ metabolic rate
- BLUE/GREEN = low activity/ metabolic rate
What are PET scans used for?
- Showcasing brain activity/ neurotransmission
- Highlighting what areas of the brain are in use/ not in use etc
What are the advantages to a PET scan?
- Valid as scan measures what it claims to measure
- Reliable as it can be repeated and same results will be found
What are the disadvantages to a PET scan?
- Radioactive tracer is invasive, can raise ethical concerns e.g. if participant can have injection safely
- Scan is claustraphobic & must be carefully explained to participant
- Expensive
- Subjective as images arent always very clear/ colours distinguishable
What does ‘MRI’ stand for?
Magnetic
Resonance
Imaging
Scan
Describe the process of an MRI scan
- Whole body in tube with noisy machine
- Person has to keep still
- Dye - contrast medium - injected to help highlight relevant areas
- Uses detection of radio frequency signals produced by displaced radiowaves in magnetic field
What are MRI scans used for?
- Identification of tumours/ lesions
- Structural
What are the advantages to an MRI scan?
- no x-rays or radioactive material used
- provides detailed view of brain
- Pretty non-invasive apart from dye
- Valid as scan results often link with what is found in reality
- Reliability due to replicability, negating subjectivity as inter-rater
What are the disadvantages to an MRI scan?
- Scan can be very stressful due to loud noise and claustraphobic setting
- Stress should be taken into consideration with patient and medical history to understand if they would react negatively
- Only provides clear images of soft tissues, not brain actitvity
- Possible reactions to the contrast agent/ dye
What does ‘fMRI’ stand for?
functional
Magnetic
Resonance
Imaging
Scan
Describe the process of an fMRI scan
- Participants’ head placed into brace to hold it still
- Loud noise and have to remain still entire time
- Works by detecting changes in oxygenation in brain e.g. more/ less blood in response to neural activity (neurons & their signals)
- When brain area more active it consumes more oxygen and to meet increased demand blood flow increases to the active area
- fMRI detects change in bloodflow to display image of brain activity
- Contrast medium e.g. dye can be used
What are fMRI scans used for?
- Highlighting what areas of the brain are in use/ not in use etc
What are the advantages to an fMRI scan?
- No risk of radiaion exposure unllike CAT or PET
- High resolution so very clear images
- Can record signals from all areas of brain not just surface cortexs’, can record signals from deep in brain
What are the disadvantages to an fMRI scan?
- Dispute over if it actualy measures what it claims as increased blood/ oxygen could be in preparation for neural activity, not because of it
- Very noisy therefore unpleasant
- Images produced extremely subjective and must be interpreted carefully as correlation doesnt imply causation
- Possible reactions to the contrast agent/ dye
Out of the 4 scanning techniques, what ones are invasive + give reasoning
- MRI scan - slightly invasive = due to dye injection for contrast medium
- fMRI scan - slightly invasive = due to dye injection for contrast medium
- PET scan - invasive = due to radioactive tracer injection
- CAT/ CT scan - slightly invasive = due to dye injection for contrast medium
Out of the 4 scanning techniques, what ones scan for brain activity?
- fMRI scan
- PET scan