Reproductive System drugs

Question 1

COCP

CI, interactions, SE, advice

Answer 1

CI- breast cancer, smoking >35 years old, migraine with aura, BMI>40, history of clot or hypertension
I- warfarin, St John’s wort, some abx, antihypertensives, antiepileptics
SE- COCP Cycle control, Occasional irregular bleeding, Clotting, CVD, cancer (breast, cyclical), pain
Advice- vomit, diarrhoea within 2 hours of the pill take another one, severe use extra precautions

Question 2

how often do you change your combined transdermal patch

Answer 2

Every 3 weeks

Question 3

POP

SE

Answer 3

SE- breast tenderness, headaches, increased appetitie, irregular bleeding, mood changes

Question 4

How long do contraceptive implants last for?

Answer 4

3 years

Question 5

Specific progestogenic IUS side effects

Answer 5

Infection
Expulsion
Perforation
Ectopic pregnancy

Question 6

IUS copper device indications, SE

Answer 6

Indications- contraception, can be inserted within 5 days of unprotected intercourse

Question 7

PDE5 inhibitors- sildenafil, verandenafil, tadalafil

Cautions, SE

Answer 7

Cautions- hypotension, recent storke, MI, unstable angina, nitrate use
SE- back pain, migraine, flushing, hypotension, visual disturbance, nasal congestion, sudden vision loss (rare)

Question 8

5A- reductase- finasteride

Indication, advice, SE

Answer 8

I- BPH
Advice- if having intercourse with woman of child bearing age they must use a condom
SE- breast cancer, loss of lipido, impotence, gynaecomastia, suicidal ideation

Question 9

Alpha-adrenoceptor blockers- Tamsulosin

Indications, cautions, SE

Answer 9

I- BPH
C- postural hypotension, micturation syncope, cataract surgery
SE- postural hypotension, erectile disorders (Such as retrograde ejactulations), intraoperative floppy iris syndrome