Reproductive physiology review Flashcards
What is the HPO axis
H: GnRH
P: FSH, LH
O: estradiol, progesterone
What ovarian hormones are more sensitive to feedback
LH: positive feedback
FSH: negative feedback
What are the two components of the menstrual cycle
Ovarian cycle: follicular and luteal phases
Uterine cycle: proliferative and secretory phases
Explain the follicular phase
Day 1-14
Estradiol is released and has positive feedback on the LH
LH surge induces ovulation
Explain the Luteal phase
Day 14-28 (endometrial proliferation)
Progesterone is released by the corpus luteum, and has negative feedback on FSH
progesterone from a dying corpus luteum induces menses to occur
What is the role of corpus luteum
produce progesterone
increase vasculature making a secretory lining
What does estradiol do
thickens the uterine wall (proliferation)
produces copious thin, clear, watery mucus making the uterus more hospitable for sperm
Explain the proliferative phase
end of menses-ovulation
Primary hormone: Estradiol
Explain the secretory phase
LH surge- onset of menses
primary hormone: progesterone
What does progesterone do
decreases mucus production making the environment thicket so sperm cant travel as well
