Reproductive infections Flashcards
PID- Eti
- Polymicrobial infection of upper tract
- Young, nulliparous, multiple sex partners
- Tb in developing countries
PID- Sx
- Uterine, adenexal & cervical motion tenderness
- Abnormal discharge
- Systemic sx
- RUQ pain
- Absence of competing dx
PID- Dx
Min dx criteria: Uterine, adenxal or CMT
- Increased temp, ban discharge, ESR, CRP adds to dx
PID- Tx
- Tx sex partner
- Cefoxitin, probenicid & doxycycline + metronidazole
Gonorrhea- Eti
- Neisseria gonorrrhoeae
- STD
- 15 - 29 YO
Gonorrhea- Sx
- Asymptomatic
- Copious discharge
- Dysuria, frequency & urgency
- Progression to cervicitis, conjunctivitis
Gonorrhea- Dx
-NAAT swab
Gonorrhea- Tx
- Ceftriaxone +
- Azithromycin or doxycycline
Syphillis- Eti
- Treponema pallidum, spirochete
- Sexual contact
- MSM
- Rate is increasing
Syphillis- Sx
1- painless chancre on genitalia, lymph enlargement
2- Maculopapular rash, lesions, weeping papules, fever, lymphadenopathy
3- Tumors, gummas, CNS disorders
Syphillis- Dx
VDRL and RPR
- Enzyme assay & CLIA, PCR
- Darkfield microscopy
Syphillis- Tx
IM penicillin G
Trichomonas vaginalis- Eti
- Protozoan infection
- Motile trichomonads
- incubation period of 5 days to 4 weeks
Trichomonas vaginalis- Sx
- Copious vaginal discharge
- Frothy yellow or green
- Pruritus, dysuria, abd pain
- Inflammation of vaginal walls & cervix
Trichomonas vaginalis- Dx
- Wet mount
- NAAT tests
- Contaminant with BV
Trichomonas vaginalis- Tx
Metronidazole or tinidazole
Genital herpes- Eto
- HSV-2
- Blacks, women, hx of STIs
- 25% adults have evidence of infection
- Recur due to stress, trauma or sun exposure
Genital herpes- Sx
- Prodrome of burning & tingling
- Small, grouped vesicles on erythematous base
- Lesions crust & heal
Genital herpes- Dx
- Viral culture, direct fluorescent Ab test
- PCR
Genital herpes- Tx
Acyclovir
Bacterial vaginosis- ETI
- Most freq. cause of vag. discharge
- Complications of pregnancy,
Bacterial vaginosis- Sx
- Vaginal discharge with fishy odor
Bacterial vaginosis- Dx
- Clinical
- Elevated pH & + sniff test
Bacterial vaginosis- Tx
- Metronidazole & clindamycin
Condylomata accumulata- Eti
- Gram negative rod, Haemophilus ducreyi
- 4-10 day incubation
Condylomata accumulata- Sx
- Chancroid lesion into pustule
- Tender, heavy foul discharge from pustule
- Inguinal adenitis
Condylomata accumulata- Dx
- Rule out other STIs
Condylomata accumulata- Tx
- Hygiene
- Azithromycin, ceftriaxone or cipro
Vulvovaginal candidiasis- Eti
- Candida infection
- Opportunistic pathogen
- Heat, moisture & occlusive clothing
Vulvovaginal candidiasis- Sx
- White, curd like discharge
- Pruritis, vulvovagnial erythema
Vulvovaginal candidiasis- Dx
KOH prep- hyphae & spores
Vulvovaginal candidiasis- Tx
- Miconazole
- Fluconozaole