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HRR 4 > Pharm- Ed > Flashcards

Pharm- Ed Flashcards

1
Q

Alprostadil- Names

A

Caverject, Muse

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2
Q

Alprostadil- Indications

A

ED

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3
Q

Alprostadil- MOA

A

Vasodilation by relaxing arterial smooth music.

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4
Q

Alprostadil- Pt Ed

A
  • Injection in lateral aspect

- Begins within 5-20 min, lasts an hour

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5
Q

Alprostadil- AE

A
  • Priapism
  • Pain & swelling
  • Penile curvature
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6
Q

Sildenafil (Viagra)- MOA

A
  • PDE-5 inhibitor, enhances effect of NO

- Increases penile blood flow

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7
Q

Tadalafil (cialis)- MOA

A
  • PDE with slower onset and longer 1/2 life
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8
Q

Sildenafil (Viagra)- AE

A
  • Color vision changes
  • nasal flushing
  • CV risk factors
  • Don’t take with nitrates, alpha blockers
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9
Q

Leuprolide- Indications

A
  • Prostate CA

- Brease CA & endometriosis

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10
Q

Leuprolide- MOA

A
  • Inhibition of synthesis of androgen and estrogen in pituitary
  • GnRH agonist
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11
Q

Flutamide- Indications

A
  • Prostate CA, in conjunction of leuprolide
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12
Q

Flutamide- MOA

A
  • Antiandrogen agent

- Competes with natural hormone binding site

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13
Q

Flutamide/ leuprolide- AE

A
  • Hot flashes, impotence & gynecomastia

- Nausea & diarrhea

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14
Q

5 alpha reductase inhibitors- Names

A

Finistride & dutasteride

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15
Q

5 alpha reductase inhibitors- MOA

A

Reduces size of prostate gland

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16
Q

5 alpha reductase inhibitors- Indications

17
Q

5 alpha reductase inhibitors- AE

A

Libido & ED

18
Q

Alpha 1 receptor blockers- Indications

A

Urinary issues associated with enlarged prostate

19
Q

Alpha 1 receptor blockers-MOA

A
  • Decreases tone in smooth muscle of bladder neck
  • Improves urine flow
  • Lowers BP in HTN
  • First pass effect (first dose can cause syncopy)
20
Q

Alpha 1 receptor blockers- Names

A

Prazosin, terazosin, alfuzosin, tamsulosin

21
Q

Alpha 1 receptor blockers- Pt ed

A
  • Take initial dose at home in bed due to first pass effect
22
Q

Incontinence drugs- names

A

Tolterodine tartrate, oxybutynin, trospium

23
Q

Incontinence drugs- MOA

A
  • Anticholinergics

- Block muscarinic receptors

24
Q

Incontinence drugs- AE

A
  • Xerostomia
  • Dizziness
  • constipation
  • Somnolence

HRR 4 (19 decks)

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