Repro Exam 3 Flashcards
How much body water (in %) can an animal lose before it dies?
10-15%
What are the 3 sources for total body water?
Drinking water, water in food, metabolic water
What are the functions of water in the body?
Solvent, transport medium, temperature regulation, participates in digestive processes, elimination of waste products
How is water lost from the body? Which method causes the most loss?
Urinary excretion = greatest loss; fecal excretion, evaporation
What is obligatory water loss?
Minimum amount of water required for the body to excrete waste products
What is facultative water loss?
Additional water excreted to maintain proper water balance
What factors affect voluntary water consumption – aka drinking?
Ambient temperature, type of diet, physiological status (health, level of exercise), water quality (taste), water temperature
What or how can we impact water consumption? (Increase it?)
Diet: abundant in water, increasing NaCl content; Increased: environmental temperatures, exercise, energy intake; tepid water preferred to cold water
For what reason(s) would we want to increase water consumption?
Diarrhea, increased: environmental temperatures, exercise and energy intake
How much of the body’s dry weight is protein?
50% or more
Large organic compounds containing carbon, hydrogen, oxygen & nitrogen; building blocks of proteins
amino acid
What is the amine group?
NH2
What is the carboxyl group?
COOH
What is the “R” group?
variant
Why are proteins considered acids?
made of amino acids ??
How many amino acids are there?
22
What is the difference between a simple and a complex protein?
Simple: contain only amino acids
Complex: simple protein combined with a non-protein molecule (ex: glycoproteins, lipoproteins)
Estimation of protein content based on nitrogen content
crude protein
Protein that can be converted to a form that can be absorbed by the animal
digestible protein
What are the functions of protein in the body?
Structural components, muscle contraction, enzymes, hormones, blood clotting, antibodies, carrier substances
Of the functions in the body, which proteins do you think are the least digestible?
Keratin, Collagen, Actin & Myosin ????????
Amino acids that must be provided in the diet
essential amino acid
What are the essential amino acids? (Memorize them)
Arginine Histidine Isoleucine Leucine Lysine Methoinine
Phyenylalanine Taurine (cats only) Tryptophan Threonine Valine
PVT. MAT(T) HILL (Matt has 2 T’s if he is a cat)
Why must proteins be part of the diet?
Provide essential amino acids for protein synthesis
Provide nitrogen for synthesis of AA & other nitrogen-containing compounds
Can protein be used as an energy source?
Yes, if energy needs are not being met w/carbohydrates and fats
What does “positive nitrogen balance” mean in regards to diet?
Intake exceeds excretion; occurs when new tissue is being synthesized
What does “negative nitrogen balance” mean?
Excretion exceeds intake
What ways can the body lose protein?
Body tissues are being catabolized to provide energy
Inadequate levels of proteins/AA are being fed
Renal or gastrointestinal disease increases losses
What does the term “high quality protein” mean?
Contains all the essential AA’s
Essential AA present in the lowest quantity in a particular feedstuff; limits body’s ability to use that particular feedstuff to make body protein
limiting amino acid
What are the most common “limiting amino acids”?
Methionine, tryptophan, lysine
How does energy density of a diet affect protein requirements?
If the diet does not contain adequate levels of energy in the form of carbohydrates and fats, proteins will be used for energy. This type of diet must contain higher levels of proteins to meet AA and nitrogen requirements.
How does energy density of a diet affect the quality of protein required?
Diets that are very energy dense must contain higher % of protein when consumed or fed to just meet energy requirements. Because of the high energy density, the animal will stop eating before it has obtained all the necessary proteins.
How much of a plant is carbohydrates? (in percentage)
60-90%
There are 2 major categories of carbohydrates, what are they?
Starches & sugars; Fiber
Which category is the most easily digested? Which is the most difficult?
Fiber most difficult; Starches & sugars most easily
In what form do animals store carbohydrates?
Glycogen
What is meant by the term monosaccharides?
Single unit sugars
Give some examples of monosaccharides and where they are found.
Glucose (prepared in corn syrup & sweet fruits)
Fructose (honey, ripe fruits, some veggies)
Galactose (not found in free form in foods)
What is meant by the term disaccharides?
Sugars made of 2 linked monosaccharide units
Give some examples and where they are found.
Lactose: milk; Sucrose: table sugar, sugar cane, beets, maple syrup
What is meant by the term polysaccharides?
Many linked monosaccharide units; starch, glycogen, fiber
Give some examples and where they are found.
Starch: commercial pet foods & cereal grains; Glycogen: liver & muscle; Fiber: plant material
Why can’t table sugar (sucrose) be used as an energy source in neonates?
They lack sucrase, the enzyme necessary to digest sucrose
Why are many adults (and most adult cats) unable to tolerate milk?
Lack lactase, enzyme necessary to digest lactose
Noncarbohydrate component of fiber, a polymer (made of long chain of linked units), non-digestible
lignan
Why is fiber hard to digest?
Contains lignan which is non-digestible; bonds between the monosaccharides in fiber are of chemical nature that resists breakdown by the enzymes of the GI tract
Why are ruminants (and other herbivores) able to “digest” fiber?
Certain microbes can break down fiber to varying degrees
The process of “digesting” fiber is called _________ and releases __________.
Fermentation; short-chain fatty acids (SCFAs)
Can monogastrics absorb SCFA’s?
Not to any significant degree
Why is fiber necessary in the diet?
Provide source of energy only to cells of colon
What effect does fiber have on energy density of a diet?
Decreases energy density of diet; useful for weight control diets
The feeling or state of being sated
Satiety
What would you expect to happen to the volume of stool in an animal fed a high fiber diet?
Increases
Do carbohydrates play a role in protein synthesis?
Yes, source of carbon for synthesis of nonessential AA’s
Synthesis of glucose by the liver
gluconeogenesis
Compare the relative carbohydrate content in feeds manufactured for livestock, dry pet foods and canned pet foods.
Livestock: large proportions
Dry pet foods: moderate amounts
Canned pet foods: little to no carbohydrates
What are the differences between fats and oils?
Fats: lipids of animal origin, except marine mammals
Oils: liquid fats usually of plant or marine mammal origin
Carboxylic acid with long hydrocarbon tails; Basic building block of fat (along w/ triglycerides & glycerol); Found in animal & plant materials
fatty acid
What are lipoproteins?
Lipid + protein
What are phospholipids?
Lipid + phosphoric acid & nitrogen
What are glycolipids?
Lipid + carbohydrate
Another term for fats & oils, make of 3 fatty acids linked to a molecule of glycerol
triglycerides
A type of fat that contains no double bonds between carbon atoms; carbon atoms saturated w/hydrogen
Saturated
a type of fat that contains 1 or more double bond between carbon atoms
Unsaturated
In human nutrition, which is the “good fat” and which is the “bad fat”?
Unsaturated = good; Saturated = bad
What has more saturated fatty acids, oils or fats?
Fats
Conversion of unsaturated fatty acids to saturated fatty acids; hydrogen is added to the molecule
transfat
What is the process by which transfats are produced?
Hydrogenation
Why does ruminant body fat contain a high percentage of saturated body fat?
Because rumen bacteria cause hydrogenation
Fat has 4 major roles in the body, what are they?
Stored energy, insulation, structural (cell membranes), nutrient transport
Fat has 3 major roles in the diet, what are they?
Source of energy and essential fatty acids (EFAs) and improves palatability and texture
How does fat affect the energy density of a diet?
Substantially increases the energy density of the food
A fatty acid that cannot be produced by the body at a rate sufficient to prevent disease & must be supplied in the diet
essential fatty acid
Linolenic acid; an EFA in cats and other species if linoleic acid is not present in sufficient concentration
arachadonic acid
What is arachadonic acid a precursor molecule for?
Linoleic acid (?)
In what species is arachadonic acid an essential fatty acid?
an EFA in cats and other species if linoleic acid is not present in sufficient concentration
What are symptoms of essential fatty acid deficiencies? There are 4 major ones.
Poor coat: hair loss & skin lesions
Decreased reproductive efficiency & lactation
Abnormal growth
Liver & kidney abnormalities in kittens
What does the term “rancid” mean?
decomposed
What makes a food become rancid?
Fats exposed to high temperatures for excessive periods undergo oxidation = rancid fat unavailable to animal
Why is vitamin E sometimes (usually) added to diets that have a high content of polyunsaturated fatty acids?
Excessive ingestion of polyunsaturated fatty acids (PUFAs) can result in an increase in the dietary vitamin E requirement
Besides being an important vitamin, why is vitamin E used in manufacturing animal feeds?
Vit E is preferentially oxidized before PUFAs, protects PUFAs from rancidity
What is one clinical syndrome that occurs when feeding diets low in vitamin E?
pansteatitis (yellow fat disease) can occur in cats
What are the clinical signs of pansteatitis?
Depression & anorexia, increased sensitivity to touch on chest and abdomen, reluctance to move
Diets made up largely of ______ can result in hypovitaminosis E.
PUFAs, primarily fish products
Why must a cat eat animal fat? (or, why can’t a cat utilize plant oils?)
The only source of arachidonic acid is animal fat
What are the criteria for being a vitamin?
Organic molecules, required in extremely small amounts, essential for normal metabolism, deficiency symptoms or illnesses result when there is not enough present in the body, cannot normally be synthesized by the body
What are the fat soluble vitamins?
A, D, E, K
What is a provitamin?
Provitamins are converted to active vitamins by animal cells
Do deficiencies of fat soluble vitamins happen rapidly or slowly?
Slowly because they can be stored in the liver and body fat
Is it possible to develop toxicities with fat soluble vitamins?
There is a potential for toxicity
What are the water soluble vitamins?
B-complex (Thiamin, riboflavin, pyridoxine, cyanocobalamin, pantothenic acid, nicotinic acid, folic acid, biotin, choline) and C (ascorbic acid)
Do deficiencies of water soluble vitamins happen rapidly or slowly?
Rapidly
Is it possible to develop toxicities with water soluble vitamins?
Toxicity unlikely since they are not stored in the body
How are water soluble vitamins eliminated from the body?
Excreted in urine
What is ascorbic acid?
Vitamin C
What does vitamin A do in the body?
Maintenance of epithelial tissues, vision, bone growth, reproduction
What is/are the sources of vitamin A?
Carotenoids, a yellow/orange pigment synthesized by plants
Most plentiful Carotenoid (provitamin A) and has the highest biological activity
Beta Carotine
Is the concentration of vitamin A higher in fresh grasses or stored hay?
Higher in fresh grasses
Why iss the concentration of vitamin A higher in fresh grasses?
Vitamin A is destroyed by oxidation
Do animal products (meat) contain vitamin A?
No, fish liver oil, milk, liver, and egg yolk may contain vit A
How are precursor vitamins converted to Vitamin A?
Enzymes in intestinal mucosa convert carotenoids to active vit A
Why do felines require actual, active vitamin A?
Felines lack the intestinal enzyme that converts carotenoids to active vit A
What are symptoms of vitamin A deficiency?
Night blindness, impaired growth, reproductive failure, loss of epithelial integrity, dermatoses, abnormal bone & tooth development
In what species would you most likely see vitamin A deficiency?
Ruminants, esp thos maintained on range only over the winter
What are symptoms of vitamin A toxicosis?
Skeletal abnormalities, skin abnormalities, anorexia & weight loss, hyperesthesia
What is vitamin D?
A group of compounds that regulates Ca and P metabolism
What is the precursor to vitamin D?
Ergosterol ergocalciferol Vit D2
Where is vitamin D activated?
Liver and kidney