Replicación Flashcards

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1
Q

En qué dirección es la replicación

A

5’-3’

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2
Q

Las 3 características de la replicación

A
  • Semiconservadora (Se conserva una hebra)
  • Bidireccional
  • Continua y discontinua
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3
Q

Helicasa

A

Rompe los puentes de hidrógeno que mantienen el superenrollamiento

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4
Q

Proteína de unión a cadena sencilla (RPA)

A

Evitan la formación de puentes de hidrógeno

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5
Q

Primasa

A

Sintetiza primers junto con la DNA polimerasa alfa.
Proporciona extremo 3’

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6
Q

Topoisomerasa

A

Corta y forma enlaces fosfodiester, deshace el superenrollamiento

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7
Q

RNAasa H1

A

Retira los primers de la hebra continua

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8
Q

Endonucleasa FLAP 1

A

Retira los primers de la hebra discontinua

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9
Q

Ligasa

A

Forma el enlace fosfodiester entre nucleótidos contiguos

Une los fragmentos

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10
Q

Telomerasa

A

Transcriptasa reversa que sintetiza DNA

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11
Q

Antígeno nuclear de proliferación celular (PCNA)

A

Mantiene todas las proteínas juntas

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12
Q

DNA polimerasas

A

alfa
beta
delta
epsilon
gamma

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13
Q

DNA pol Alfa

A

primasa (pone nucleótidos)

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14
Q

DNA pol beta

A

Repara errores

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15
Q

DNA pol delta

A

Elongación de la hebra resagada

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16
Q

DNA pol epsilon

A

Elongación de la hebra continua

17
Q

DNA pol gamma

A

Sólo actúa en la mitocóndria

18
Q

DNA pol gamma

A

Sólo actúa en la mitocóndria