RegulaciĆ³n del mRNA Flashcards

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1
Q

QuƩ son los miRNA

A

micro RNA
- Regula la expresiĆ³n de RNAm

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2
Q

Por quƩ son sintetizados los miRNA

A

por el RNA pol II (CAP y cadena de Poli A)

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3
Q

Corte 1:

A

Sucede en el nĆŗcelo:
- Se corta la cola de Poli A y CAP

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4
Q

Corte 2:

A

Sucede en el citosol
- Se corta el bucle
- Quedan dos hebras

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5
Q

RISC:

A

Complejo silenciador
- Escoge una hebra y lo lleva a un UTR3ā€™ de un RNAm

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6
Q

Que contiene el complejo RISC y quƩ hace

A

Argonauta
- Si se complementa el miRNA con el RNAm = argonauta corta el RNAm

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7
Q

QuƩ degrada las dos partes cortadas por la argonauta?

A

Exonucleasas

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8
Q

QuƩ pasa si no se complementa al 100% el miRNA y el RNAm

A

El RNAm se lleva a los cuerpos P

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9
Q

QuƩ hay en los cuerpos P

A

Exonucleasas y deadenilasas

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10
Q

Que hacen los siRNAs

A

Evitan el paso de secciones de genes de cromosoma a cromosoma = mutaciones (evita mutaciones) Esto es un transposon
- Nos protegen de los transposones

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