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MRCS med school > Renal tumours > Flashcards

Renal tumours Flashcards

1
Q

Types of renal tumour

A

Renal Cell Carcinoma

Transitional Cell Carcinoma

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2
Q

Risk factors for renal cell carcinomas

A

> 55 yrs

M

Obesity

Smoking

HTN

Dialysis

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3
Q

What type of cell is renal cell carcinoma

A

Adenocarcinoma from proximal renal tubular epithelium

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4
Q

Presentation of renal cell carcinoma

A

Triad:

  • Haematuria
  • Loin pain
  • Loin mass
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5
Q

Paraneoplastic features of renal cell carcinoma

A

EPO - polycythaemia

PTHrP - hypercalcaemia

Renin - HTN

ACTH - cushing’s

Amyloidosis

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6
Q

PTHrP

A

Parathyroid related protein

Secreted by some cancers

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7
Q

Metastasis sites of renal cell carcinoma

A

Bone

Liver

Lung

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8
Q

CXR for renal cell carcinoma

A

lung cannonball mets

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9
Q

IV urogram result for renal cell carcinoma

A

filling defect

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10
Q

IVU

A

Intravenous urogram

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11
Q

Robson staging of renal cell carcinoma

A
  1. Confined to kidney
  2. Involves perinephric fat, but not Garota’s fascia
  3. Spread into renal vein
  4. Spread to adjacent / distant organs
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12
Q

Garota’s fascia

A

a layer of connective tissue encapsulating the kidneys and the adrenal glands

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13
Q

Medical Mx of renal cell carcinoma

A

Reserved for pts with poor prognosis

Temsirolimus - mTOR inhibitor

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14
Q

Surgical Mx of renal cell carcinoma

A

Radical nephrectomy

Partial nephrectomy

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15
Q

Risk factors for transitional cell carcinomas

A

> 50 yrs

M

Smoking

Amine exposure (rubber industry)

Cyclophosphamide (chemo agent)

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16
Q

Locations for transitional cell carcinomas

A

Bladder

Ureter

Renal pelvis

17
Q

Presentation of transitional cell carcinoma

A

Painless haematuria

Frequency, urgency, dysuria

Urinary tract obstruction

18
Q

IVU result for transitional cell carcinoma

A

pelviceal filling defect

19
Q

Mx of transitional cell carcinoma

A

Nephrouretectomy

20
Q

Association of Squamous Cell Carcinoma

A

Chronic infected staghorn calculi

Schistosomiasis

MRCS med school (44 decks)

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