Renal tubular acidosis Flashcards
1
Q
what is the defect in type 1 RTA?
A
- ability of a intercalated cells to secrete protons
- no new HCO3 generated
2
Q
what is the defect in type 2 RTA?
A
- PCT HCO3 reabsorption
- metabolic acidosis
3
Q
what is the defect in type 4 RTA?
A
- hypoaldosteronism: low ammonia synthesis in PCT - decreased ammonium secretion
4
Q
type 1 RTA is associated with ______________ (hypokalemia / hyperkalemia)
A
hypo
5
Q
type 2 RTA is associated with ______________ (hypokalemia / hyperkalemia)
A
hypo
6
Q
type 4 RTA is associated with ______________ (hypokalemia / hyperkalemia)
A
hyper
7
Q
amphotericin B can cause what type of RTA?
A
type 1
8
Q
aldosterone resistance or decreased aldosterone production can lead to what type of RTA?
A
type 4
9
Q
fanconi anemia can lead to what type of RTA?
A
type 2
10
Q
carbonic anhydrase inhibitors can lead to what type of RTA?
A
type 2
