Familial dysplipidemias Flashcards
1
Q
what is increased in hyperchylomicronemia?
A
- chylomicrons
- TGs
- cholesterol
2
Q
what is increased in familial hypercholesterolemia?
A
- LDL
- cholesterol
3
Q
what is increased in hyperTG?
A
- VLDL
- TGs
4
Q
what is deficient in hyperchylomicronemia?
A
lipoprotein lipase or altered apolipoprotein C-II
5
Q
what is deficient in familial hypercholesterolemia?
A
absent or defective LDL receptors
6
Q
what is deficient in hyperTG?
A
hepatic overproduction of VLDL (mostly TGs)
7
Q
what is the inheritance of hyperchylomicronemia?
A
AR
8
Q
what is the inheritance of familial hypercholesterolemia?
A
AD
9
Q
what is the inheritance of hyperTG?
A
AD
10
Q
- pancreatitis
- hepatosplenomegaly
- eruptive / pruritic xanthomas
- creamy layer in supernatant
- no increased risk of atherosclerosis
A
hyperchylomicronemia
11
Q
- accelerated atherosclerosis
- xanthomas
- corneal arcus
A
familial hypercholesterolemia
12
Q
hyperTG can lead to what condition?
A
acute pancreatitis
