Important genes of embryogenesis Flashcards
1
Q
function(s) of sonic hedgehog?
A
- patterning along AP axis
- CNS development
2
Q
function(s) of Wnt-7?
A
organization along dorsal-ventral axis
3
Q
function(s) of FGF?
A
lengthening of limbs
4
Q
function(s) of homeobox (Hox)?
A
segmental organization of embryo in a craniocaudal direction
5
Q
mutation in what gene can lead to holoprosencephaly?
A
sonic hedgehog
6
Q
a patient with appendages in the wrong places likely has a mutation in what gene?
A
homeobox (Hox)
7
Q
syndactyly and polydactyly is a response to mutation in what gene?
A
homeobox (Hox)
8
Q
what do homeobox (Hox) genes code for?
A
DNA binding transcription factors
9
Q
segmental organization of embryo in a craniocaudal direction
A
homeobox (Hox)
10
Q
lengthening of limbs
A
FGF
11
Q
organization along dorsal-ventral axis
A
Wnt-7
12
Q
- patterning along AP axis
- CNS development
A
sonic hedgehog
