RENAL SYSTEM Flashcards

1
Q

The kidneys are situated against the dorsal body wall
in a _____

A

retroperitoneal position (behind the parietal peritoneum)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

 The kidneys are situated at the level of the ___

A

T12 to L3
vertebrae

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

 The right kidney is slightly ___

A

lower than the left

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

provides each kidney with arterial blood
supply

A

Renal artery

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

 Each nephron consists of two main structures

A
  1. Renal corpuscle
  2. Renal tubule
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Renal corpuscle consists

A

Glomerulus
Glomerular (Bowman’s) caps

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

 Renal artery divides into

A

segmental arteries →
interlobar arteries → arcuate arteries → cortical
radiate arterie
SIAC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Foot processes cling to the glomerulus

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

a knot of capillaries made of podocytes

A

Glomerulus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Structural and functional units of kidneys

A

NEPHRONS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

From the glomerular (Bowman’s) capsule, the
subdivisions of the renal tubule are:

A
  1. Proximal convoluted tubule (PCT)
  2. Nephron loop (loop of Henle)
  3. Distal convoluted tubule (DCT
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

make up the inner (visceral) layer of the glomerular capsule

A

Podocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

 Located entirely in the cortex
 Include most nephron

A

Cortical nephrons

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

cup-shaped
structure that surrounds the glomerulus
 First part of the renal tubule

A

Glomerular (Bowman’s) caps

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

 Found at the cortex-medulla junction

A

Juxtamedullary nephrons

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

 Extends from glomerular capsule and ends when it
empties into the collecting duct

A

Renal tubule

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

create a porous membrane—ideal for filtration

A

Filtration slits

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

 Collecting ducts collect urine from both types of
nephrons, through the renal pyramids, to the calyces,
and then to the renal pelvis

A

Juxtamedullary nephrons

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

—arises from a cortical radiate artery
and feeds the glomerulus

A

Afferent arteriole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

 Nephron loop dips deep into the medulla

A

Juxtamedullary nephrons

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

 Fed and drained by arterioles

A

Glomerulus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

—receives blood that has passed
through the glomerulus

A

Efferent arteriole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Filtrate leaves via the

A

renal tubule

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Specialized for filtration

A

Glomerulus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Urine formation is the result of three processes
1. Glomerular filtration 2. Tubular reabsorption 3. Tubular secretion
3
 High pressure forces fluid and solutes out of blood and into glomerular capsule
Glomerulus
3
is a nonselective, passive process in which fluid passes from the blood into the glomerular capsule part of the renal tubule
Glomerular filtration
3
Water and solutes smaller than proteins are forced through glomerular capillary walls
3
Proteins and blood cells are normally too large to pass through the filtration membrane
3
Once in the capsule, the fluid is called
filtrate
3
Filtrate will be formed as long as systemic blood pressure is normal
3
 The peritubular capillaries reabsorb useful substances from the renal tubule cells, such as:
Tubular reabsorption  Water  Glucose  Amino acids  Ions
3
 If arterial blood pressure is too low, filtrate formation stops because glomerular pressure will be too low to form filtrate
3
Most reabsorption occurs in the
proximal convoluted tubule
3
Some reabsorption is passive; most is active (ATP)
3
 Reabsorption in reverse  Some materials move from the blood of the peritubular capillaries into the renal tubules to be eliminated in filtrate  Hydrogen and potassium ions  Creatinine Secretion is important for:  Getting rid of substances not already in the filtrate  Removing drugs and excess ions  Maintaining acid-base balance of blood  Materials left in the renal tubule move toward the ureter
Tubular secretion
3
Nitrogenous waste products are poorly reabsorbed, if at all  Tend to remain in the filtrate and are excreted from the body in the urine
Nitrogenous waste
3
 —associated with creatine metabolism in muscles
Creatinine
3
In 24 hours, about ___ liters of urine are produced
1.0 to 1.8
3
 —end product of protein breakdown
Urea
3
—results from nucleic acid metabolism
Uric acid
3
 Urine is what remains after the filtrate has lost most of its water, nutrients, and necessary ions through reabsorption  Urine contains nitrogenous wastes and substances that are not needed
3
Filtrate contains everything that blood plasma does (except proteins)
3
Normal urine output is
30 to 60mL per HOUR
3
Yellow color is normal and due to the pigment ___ (from the destruction of hemoglobin) and solutes
urochrome
3
Solutes NOT normally found in urine
 Glucose  Blood proteins  Red blood cells  Hemoglobin  WBCs (pus)  Bile
3
Nonpathological: Physical exertion, pregnancy Pathological: Glomerulonephritis, hypertension
Proteinuria (pro″te-˘ı-nu′re-ah) (also called albuminuria)
4
Urine specific gravity of
1.010 to 1035
4
Solutes normally found in urine
 Sodium and potassium ions  Urea, uric acid, creatinine  Ammonia  Bicarbonate ion
4
Nonpathological: Excessive intake of sugary foods Pathological: Diabetes mellitus
Glycosuria
4
Urinary tract infection
Pyuria (pi-u′re-ah)
4
Bleeding in the urinary tract (due to trauma, kidney stones, infection)
Hematuria (he″mah-tu′re-ah)
5
Various: Transfusion reaction, hemolytic anemia
Hemoglobinuria (he″mo-glo-b˘ı-nu′re-ah)
6
Liver disease (hepatitis)
Bilirubinuria (bil″˘ı-roo-b˘ı-nu′re-ah)
6
7
8
9
10
11
11
12
12
13
13
14
15
16
16
17
17
18
18
19
19
19
20
21
21
22
23
23
24
25
25
26
27
27
27
28
28
28
29
30
30
30
30
31
32
32
32
33
33
33
34
34
35
36
36