Renal Response To Acidosis And Alkalosis

Question 1

Acidosis develops when

Answer 1

The normal plasma buffer mechanisms are stressed by excessive hydrogen ions

Question 2

The renal contribution remains limited to

Answer 2

1. The secretion of hydrogen
2. the activity of buffers in the tubular fluid
3. the removal of CO2
4. the reabsorption of NAHCO3

Question 3

How do the tubule cells bolster the capabilities of the carbonic acid bicarbonate buffer system

Answer 3

1. By increasing the concentration of bicarbonate ions in the ECF;
2. In a starving person, they break down amino acids, yielding ammonium ions that are pumped into the tubular fluid, bicarbonates to help buffer Ketone bodies in the blood, and carbon chains for catabolism.

Question 4

When alkalosis develops

Answer 4

1. The rate of hydrogen secretion by the kidneys declines
2. Tubule cells do not reclaim the bicarbonates in tubular fluid
3. The collecting system transports HC03 into tubular fluid while releasing a strong acid HCl into Peritubular fluid

Question 5

The results of renal response to alkalosis

Answer 5

The concentration of HC03 in blood decreases, promoting the dissociation of H2CO3 and the release of hydrogen ions.
The additional hydrogen generated by the kidneys help return the pH to normal