Metabolic Alkalosis Flashcards
Metabolic alkalosis occurs when bicarbonate concentrations are elevated
The bicarbonate ions then interact with hydrogen ions in solution, forming H2CO3. The resulting decrease in hydrogen concentrations cause signs of alkalosis.
Metabolic alkalosis is rare one interesting cause is known as alkaline tide
Alkaline tide is due to influx into the ECF of large numbers of bicarbonate ions associated with the secretion of hydrochloric acid by the gastric mucosa
Alkaline tide
- Temporarily increases the bicarbonate concentration in the ECF during meals.
- Repeated vomiting may bring on serious metabolic alkalosis because the stomach continues to generate stomach acids to replace those that are lost.
- As a result the bicarbonate concentration of the ECF continues to increase
Compensation for metabolic alkalosis
Involves a decrease in the breathing rate, coupled with an increased loss of bicarbonate in Urine
Treatment of mild cases
Controlling the vomiting
Administering solutions that contain NaCl or KCl
Treatment of acute cases of metabolic acidosis
- Administering ammonium chloride (NH4CL)
- Ammonium chloride leads to the internal generation of HCL.
- As the HCl diffuses into the bloodstream, pH falls to normal levels.