Renal Protein Channels Flashcards
Na/H+ antiport
PCT and early DCT
Na/Cl antiport
DCT - early proximal
Na/H antiport
Distal convoluted tubule - early proximal
H+ ATPase pump
Principal cells of distal convoluted tubule
Na/ K+ ATPase basolateral antiport
Principal cells of distal convoluted tubule
AND
most parts of all nephron
Secretion of acid H+ and Cl-
Alpha intercalated cells of DCT
Cl/HCO3- basolateral antiport
Alpha intercalated cells of DCT
HCO3- secretion
Beta intercalated cells of distal convoluted tubule
Cl-/HCO3- luminal antiport
Beta intercalated cells of distal convoluted tubule.
Mannitol targets
glomerulus
Aldosterone works by inserting Na+/K+ ATPase pumps in basolateral membrane at
collecting duct
Angiotensin II stimulates reabsorption of Na+ in
the proximal convoluted tubule
Atrial Natriuretic Peptide acts to decrease Na+ reabsorption at
the collecting duct
Na/K ATPase active transport antiport basolaterally
PCT (and throughout nephron?)