Renal Medicine Flashcards

1
Q

NICE criteria for AKI

A

Rise in creatinine of >25 in 48hrs
Rise in creatinine of >50% in 7 days
Urine output of 6h

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2
Q

AKI risk factors

A
CKD
HF
DM
Liver dx
old age
cognitive impairment
nephrotoxic meds - NSAIDS and ACE-inh
contrast medium
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3
Q

Px of CKD

A
asymptomatic usually
pruritus
anorexia
nausea
oedema 
muscle cramps
peripheral neuropathy
pallor 
HTN
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4
Q

Name 1 complication of CKD

A

anaemia
renal bone disease
CVS dx
periph. neurop.

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5
Q

Indications for dialysis

A
AEIOU
Acidosis
Electrolyte abnormalities
Intoxication
Oedema
Uraemia
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6
Q

Three types of maintenance dialysis

A
  • Continuous ambulatory peritoneal dialysis
  • haemodyalysis
  • automated peritoneal dialysis
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7
Q

Alternative to dialysis?

A

Transplant

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8
Q

Which type of syndrome must fulfil the following

  • peripheral oedema
  • proteinuria
  • serum albumin
  • hypercholesterolemia
A

NEPHROTIC SYNDROME

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9
Q

What are the types of glomerulonephritis?

A
  • Minimal change disease
  • Focal segmental glomerulosclerosis
  • Membranous glomerulonephritis
  • IgA nephropathy (AKA mesangioproliferative glomerulonephritis or Berger’s disease)
  • Post streptococcal glomerulonephritis (AKA diffuse proliferative glomerulonephritis)
  • Mesangiocapillary glomerulonephritis
  • Rapidly progressive glomerulonephritis
  • Goodpasture Syndrome
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10
Q

What are most types of glomerulonephritis treated with>

A
Immunosuppression (steroids) 
BP control (ACE-i or ARB) 
  • check 0tofinals
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11
Q

what does diabetic nephropoathy cause?

A

glomerulosclerosis cause of high sugar levels passing

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12
Q

What can a hypersensitvity reaction to drugs or infection cause in the kidney?

A

acute interstitial nephritis

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13
Q

Management of acute tubular necrosis?

A

supportive,
IV fluids
stop nephrotoxic meds
treat complications

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14
Q

Which types of Renal tubular acidosis are most relevant to clinical practice

A

1 and 4

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15
Q

How is T1 RTA treated?

T4?

A

bicarbonate

fludrocortison (+Nabicarb)

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16
Q

HUS - how is it caused?

A

E.coli 0157 causes gastroenteritis, 5 days later HUS

17
Q

How is HUS treated?

A

medical emergency - 10% mortality

supportive + antihypertensives, blood transfusions, dialysis

18
Q

What is released in rhabdomyolysis

A

Myoglobin
Potassium
Phosphate
Creatinine Kinase

19
Q

Causes of rhabdomyolysis

A

prolonged immobility, extremely rigorous exercise, crush injuries
seizures

20
Q

What causes red-brown urine and oedema?

A

Rhabdomyolysis

21
Q

ECG signs of hyperkalaemia

A

tall peaked t waves, flattened/absent P waves, broad QRS

22
Q

How is hyperkalaemia treated?

A

insulin and dextrose infusion and calcium gluconate

also
nebulised salbutamol
fluids
oral Ca resonium 
sodium bicarb
dialysis
23
Q

Extrarenal manifestations of autosomal dominant PKD

A
cerebral aneurysm
hep., splenic, panc., ovarian and prostatic cysts
mitral regurg. 
colonic diverticula
aortic root dilatation.
24
Q

Treatment of PKD

A

Tolvaptan in certain situations

AntiHTN
Analgesia
Abx
dialysis
renal tpx.