Opthalmology Chapter 1 Flashcards
Zero to medicine
Open Angle Glaucoma - OAG -> define glaucoma
optic nerve damage caused by significant intraocular pressure
Why is the OAG pressure build up slow and gradual?
gradual increase in resistance through trabecular meshwork
Why is closed angle glaucoma an emergency?
The iris seals off the trabecular meshwork -> no fluid can get through causing pressure build up
What’s a sign of glaucoma? What’s a (late) symptom?
Cupping - wider and deeper optic cup Tunnel vision (peripheral affected first)
Which med is first line in Glaucoma?
Prostaglandin analogue eyedrops - latanoprost
What’s the emergency management for CAG?
Pilocarpine -> miotic (constriction) agent
Acetazolamide ->carbonic anhydrase inhibitor (reduces aqueous humour)
Definitive treatment is Laser iridotomy
Name one drug causing CAG
Adrenergic meds - noradrenaline
Anticholinergics - Oxybutinin, solifenacin
Tricyclic antidepressants - amitriptyline
What is the most common cause of blindness in the UK?
Age-related macular degeneration
What percentage of age-rel. mac. degen. are dry?
10%
Wet has worse prognosis
Early sign of ARMDeg.
larger and greater numbers of drusen
What’s the key target of meds for wet ARMdeg?
vascular endothelial growth factor
Which part of the visual field is lost in ARMdegen
central visual field
How do you classify diabetic retinopathy
non-proliferative (background) vs proliferative
Complications of diabetic retin.
Retinal detachment, vitreous haemorrhage, rebeosis iridis, optic neuropathy, cataracts
What is a sign of hypertensive retinopathy?
Silver/copper wiring, cotton wool spots, hard exudates, retinal haemorrhages