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Renal I > Renal Histology - Olinger > Flashcards

Renal Histology - Olinger Flashcards

1
Q

2 Parts of the renal corpuscle?

A

Glomerulus

Bowman’s capsule

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2
Q

3 Parts of the renal tubule?

A

PCT
Loop of Henle
DCT - macula densa

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3
Q

Characteristics of cortical nephron

A

Located in the outer region of the cortex
Short loop of Henle
Peritubular capillary network

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4
Q

Characteristics of juxtamedullary nephron

A

Loop of Henle is long

Vasa recta

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5
Q

Glomerulus capillaries

A

Lined by fenestrated epithelial cells

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6
Q

Mesangium

A

Part of glomerulus
Mesangial cells and matrix
Shit ton of functions

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7
Q

Functions of mesangium

A

Specialized pericytes
Characteristics of smooth m and macrophages
Contractile - regulate blood flow
Capable of proliferation
Synthesize bone matrix and collagen
Mechanical support to glomerular capillaries
Control turnover of glomerular basal lamina material (phagocytic)
Secrete prostaglandins and endothelins
Responds to angiotensin II

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8
Q

Parietal layer of capsule of Bowman

A

Associated with the surrounding connective tissue
Basement membrane
Squamous epithelial cells - continuous with simple squamous epithelium of PCT

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9
Q

Visceral layer of capsule of Bowman

A

Surrounds the glomerular capillaries
Basement membrane
Podocytes

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10
Q

Urinary space

A

Located between visceral and parietal layers of glomerulus

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11
Q

Characteristics of podocytes

A

Part of visceral layer of glomerulus
Encircle the glomerular capillaries
End as pedicles

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12
Q

What comprises the glomerular filtration system

A

Podocytes
Fenestrated epithelium of the glomerular epitheliums
Basement membrane

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13
Q

Characteristic of PCT?

A 
Simple cuboidal epithelium
Apical tight junctions
Well developed apical brush border of microvilli
Lysosomes at the apical domain
Basal infoldings and interdigitations
Basal mitochondria
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14
Q

Who LOVES renal?

A

WE DO!!!

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15
Q

Which part of the loop of Henle is impermeable to water?

A

Ascending limb

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16
Q

Thick segment epithelium?

A

Low simple cuboidal epithelium

17
Q

Thin segment epithelium?

A

Simple squamous epithelium

18
Q

2 functions of interstitial cells

A

Maintenance of renal architecture

Produces erythropoietin

19
Q

Characteristics of DCT

A

Low simple cuboidal epithelium
Apical tight junctions
Lack an apical brush border of microvilli
Basal infoldings and interdigitations

20
Q

3 Parts of juxtaglomerular apparatus

A

Macula densa
Extraglomerular mesangial cells
Juxtaglomerular cells

21
Q

Juxtaglomerular cells

A

Modified smooth muscle cell of the afferent arteriole

Produces renin

22
Q

How to tell PCT from DCT?

A

PCT has abundant lysosomes and brush border with microvilli

23
Q

Characteristics of principle cells?

A

Single apical non-motile cilium

Act as a mechanosensor of fluid flow

24
Q

2 cell types of collecting tubule?

A

Principle

Intercalated

25
Q

Blood supply to kidney?

A

Segmental a –> interlobar a –> arcuate a –> interlobular a –> afferent arterioles –> glomerulus –> efferent arterioles

26
Q

2 different capillary networks?

A

Peritubular

Vasa recta

27
Q

Characteristics of peritubular capillary network?

A

Associated with cortex
Surround the cortical segments of the superficial uriniferous tubules
Lined by fenestrated epithelium cells

28
Q

Venous drainage?

A

Peritubular cap network –> interlobular v –> arcuate v –> interlobar v

29
Q

Vasa Recta

A

Drain efferent arterioles near the cortico-medullary junction
Arterial cap lined with continuous endothelial cells
Extends into the medulla
Ascending venous cap with fenestrated endothelial cells

30
Q

Medullary Rays

A

Forms the axis of a renal lobule

31
Q

Urothelium

A

Lines bladder - transitional epithelium

32
Q

Prostatic urethra epithelium

A

Transitional

33
Q

Membranous and spongy (penile) urethra epithelium

A

Pseudostratified

34
Q

Female urethra epithelium

A

Stratified squamous

Renal I (20 decks)

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