Regulation of K, Ca, PO, Mg - McCormick Flashcards
Normal range of potassium?
3.5 - 5 mEq/l
Extracellular K effects?
Resting membrane potential and excitability of muscle and nerve tissue
How does low K effect resting membrane potential?
It is lower, so it takes more work to get it to threshold
High - potential is higher than normal
Low K effects on EKG?
Low T wave
High U wave
High K effects on EKG?
High T wave
Prolonged PR interval
What is a huge list of things that can move K from ICF to ECF?
Hypokalemia Acidemia Hyperosmolality Ischemia - cell damage Heavy exercise
List of things that can move K from ECF to ICF?
Hyperkalemia
Alkemia
B-adrenergic agonists
Insulin
What cell exerts physiological control over potassium concentration?
Principal cells in collecting duct
5 Factors affect K secretion in CD?
Extracellular K conc
Na reabsorption - negative luminal voltage attracts K
Luminal fluid flow rate - dilution of secreted K
Extracellular pH - K and H exchange across cell membranes
Aldosterone - K secretion in CD