Regulation of K, Ca, PO, Mg - McCormick Flashcards

1
Q

Normal range of potassium?

A

3.5 - 5 mEq/l

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2
Q

Extracellular K effects?

A

Resting membrane potential and excitability of muscle and nerve tissue

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3
Q

How does low K effect resting membrane potential?

A

It is lower, so it takes more work to get it to threshold

High - potential is higher than normal

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4
Q

Low K effects on EKG?

A

Low T wave

High U wave

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5
Q

High K effects on EKG?

A

High T wave

Prolonged PR interval

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6
Q

What is a huge list of things that can move K from ICF to ECF?

A
Hypokalemia
Acidemia
Hyperosmolality
Ischemia - cell damage
Heavy exercise
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7
Q

List of things that can move K from ECF to ICF?

A

Hyperkalemia
Alkemia
B-adrenergic agonists
Insulin

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8
Q

What cell exerts physiological control over potassium concentration?

A

Principal cells in collecting duct

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9
Q

5 Factors affect K secretion in CD?

A

Extracellular K conc
Na reabsorption - negative luminal voltage attracts K
Luminal fluid flow rate - dilution of secreted K
Extracellular pH - K and H exchange across cell membranes
Aldosterone - K secretion in CD

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