Body Fluids Integrative Session - McCormick

Question 1

Isosmotic volume contraction/expansion

Answer 1

Osmolality stays same in both

ECF volume increases

Question 2

Example of isosmotic fluid loss

Answer 2

Vomiting or diarrhea

Question 3

Hyperosmotic volume contraction - loss of water

Answer 3

Ex. dehydration
Osmolarity of ECF would I, volume would decrease
ICF would give fluid, so vol would D and osm would I

Question 4

Examples of hyper osmotic volume contraction from loss of water?

Answer 4

Dehydration, diabetes insipidus

Question 5

Hyperosmotic volume contraction - gain of NaCl

Answer 5

Ex. eat 3 bags of chips, mannitol
ECF volume and Osm would increase
ICF vol would decrease and Osm would increase

Question 6

Hyposmotic volume contraction - loss of NaCl

Answer 6

Ex. on diuretics too long
ECF vol and Osm would decrease
Osm of ICF would decrease (losing NaCl)
volume would increase

Question 7

Hyposmotic volume expansion - gain of water

Answer 7

ECF volume would increase, Osm would decrease
ICF would increase because equilibrium
ex. SIADH, psychogenic polydipsia

Question 8

How would a dehydrated body compensate?

Answer 8

Osmoregulatory - most sensitive
– ADH, thirst
Volume systems - this has to increase 10-15%
– SNS, RAAS, ANP (retain Na+)

Question 9

Can you fix a problem with just thirst alone?

Answer 9

Nope.

Need thirst

Question 10

Predict changes in runner
ADH
Thirst
SNS
RAAS
ANP

Answer 10

ADH - I
Thirst - I
SNS - I
RAAS - I
ANP - D!! This one is different, want to retain Na+ so you retain water

Question 11

Sweating leads to?

Answer 11

Increased thirst and ADH release to replace water loss