Acid Base - AG - CIS - McCormick Flashcards
Is compensation for acid base problems ever complete?
Nope.
Causes of metabolic acidosis? Normochloremic
Diarrhea
Renal tubular dysfunction
Carbonic anhydrase
Addison’s
Causes of metabolic alkalosis?
Vomiting Hypokalemia Diuretic abuse Contraction alkalosis Loop diuretics Primary hyperaldosteronism Chronic K loss
Causes respiratory acidosis?
Hypoventilation
COPD
Restrictive lung disease
How can you tell if an acid-base imbalance is acute or chronic?
Acute - pH will not be normalized
What causes numbness and tingling in hands in acid-base imbalance?
Decreased free or ionized plasma calcium due to alkalemia
H competes with Ca2 for binding sites
Acidemia’s result on free plasma Ca2
Increased
Alkalemia’s result on free plasma Ca2?
Decreased
Causes of acute respiratory alkalosis
Hyperventilation anxiety pregnancy sepsis salicylates liver failure CHF Common in critically ill --esp on mechanical vent
What is common with massive MI?
Lowered tissue perfusion that allows for build up of waste products, especially lactate
Reduced pulmonary blood flow hampers ability to compensate for metabolic acidosis