Renal Disease Flashcards

1
Q

Symptoms of this disease usually occur in children and young adults following respiratory infections caused by group A Strep with M protein in the cell wall

A

Acute Poststreptococcal Glomerulonephritis

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2
Q

Glomerular disorder defined by deposition of immune complexes in the glomerulus as a complication of systemic immune disorders

A

Rapidly Progressive (Crescentic) Glomerulonephritis

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3
Q

In Goodpaster Syndrome, attachment of the ____ to the basement membrane, followed by complement activation, produces capillary destruction.

A

Antiglomerular basement membrane antibody

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4
Q

TRUE or FALSE: Goodpasture Syndrome progression to chronic glomerulonephritis and end-stage renal failure is common.

A

True

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5
Q

What is the disease which causes a granuloma-producing inflammation of the small blood vessels?

A

Wegener’s Granulomatosis

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6
Q

Testing for ANCA includes incubating the patient’s serum with either ethanol or ____.

A

Formaldehyde-fixed neutrophils

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7
Q

If neutrophils are fixed with ethanol the antibodies form a ____ pattern called p-ANCA.

A

Perinuclear

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8
Q

If neutrophils are fixed with formalin/formaldehyde, the pattern is ____ called c-ANCA.

A

Granular

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9
Q

This disease is characterized by a pronounced thickening of the glomerular membrane resulting from the deposition of IgG complexes

A

Membranous Glomerulonephritis

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10
Q

In Membranous Glomerulonephritis, there is a tendency to ____.

A

Thrombosis

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11
Q

Which type of MPGN displays increased cellularity in the subendothelial cells of the mesangium?

A

Type 1

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12
Q

Which type of MPGN displays extremely dense deposits in the glomerular membrane?

A

Type 2

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13
Q

In MPGN, type 1 patients progress to ____, and type 2 progress to ____.

A

Nephrotic syndrome; chronic glomerulonephritis

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14
Q

What is the most common cause of glomerulonephritis?

A

IgA nephropathy

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15
Q

TRUE or FALSE: In Nephrotic Syndrome, the ensuing hypoalbuminemia appears to stimulate increased lipid production by the liver.

A

True

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16
Q

What are the immune deposits are frequently found in Focal Segmental Glomerulonephritis?

A

IgM & C3

17
Q

This disease is often seen in association with abuse of heroin, analgesics and with AIDS

A

FSGS

18
Q

What is the most common cause of end-stage renal disease?

A

Diabetic Nephropathy

19
Q

In inherited renal glucosuria, either the ____ in the tubules is decreased, or the ____ for glucose is decreased.

A

Number of glucose transporters; affinity of the transporters

20
Q

____ most frequently occurs as a result of ascending movement of bacteria from a lower UTI into the renal tubules & interstitium.

A

Pyelonephritis

21
Q

Symptoms of AIN tend to develop approximately ____ following administration of medication.

A

2 weeks

22
Q

This is a procedure using high-energy shock waves which can break stones located in the upper UT

A

Lithiotripsy