Renal Disease Flashcards
Symptoms of this disease usually occur in children and young adults following respiratory infections caused by group A Strep with M protein in the cell wall
Acute Poststreptococcal Glomerulonephritis
Glomerular disorder defined by deposition of immune complexes in the glomerulus as a complication of systemic immune disorders
Rapidly Progressive (Crescentic) Glomerulonephritis
In Goodpaster Syndrome, attachment of the ____ to the basement membrane, followed by complement activation, produces capillary destruction.
Antiglomerular basement membrane antibody
TRUE or FALSE: Goodpasture Syndrome progression to chronic glomerulonephritis and end-stage renal failure is common.
True
What is the disease which causes a granuloma-producing inflammation of the small blood vessels?
Wegener’s Granulomatosis
Testing for ANCA includes incubating the patient’s serum with either ethanol or ____.
Formaldehyde-fixed neutrophils
If neutrophils are fixed with ethanol the antibodies form a ____ pattern called p-ANCA.
Perinuclear
If neutrophils are fixed with formalin/formaldehyde, the pattern is ____ called c-ANCA.
Granular
This disease is characterized by a pronounced thickening of the glomerular membrane resulting from the deposition of IgG complexes
Membranous Glomerulonephritis
In Membranous Glomerulonephritis, there is a tendency to ____.
Thrombosis
Which type of MPGN displays increased cellularity in the subendothelial cells of the mesangium?
Type 1
Which type of MPGN displays extremely dense deposits in the glomerular membrane?
Type 2
In MPGN, type 1 patients progress to ____, and type 2 progress to ____.
Nephrotic syndrome; chronic glomerulonephritis
What is the most common cause of glomerulonephritis?
IgA nephropathy
TRUE or FALSE: In Nephrotic Syndrome, the ensuing hypoalbuminemia appears to stimulate increased lipid production by the liver.
True
What are the immune deposits are frequently found in Focal Segmental Glomerulonephritis?
IgM & C3
This disease is often seen in association with abuse of heroin, analgesics and with AIDS
FSGS
What is the most common cause of end-stage renal disease?
Diabetic Nephropathy
In inherited renal glucosuria, either the ____ in the tubules is decreased, or the ____ for glucose is decreased.
Number of glucose transporters; affinity of the transporters
____ most frequently occurs as a result of ascending movement of bacteria from a lower UTI into the renal tubules & interstitium.
Pyelonephritis
Symptoms of AIN tend to develop approximately ____ following administration of medication.
2 weeks
This is a procedure using high-energy shock waves which can break stones located in the upper UT
Lithiotripsy
