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GU > Renal cell carcinoma/ Wilms Tumour / Bladder Cancer > Flashcards

Renal cell carcinoma/ Wilms Tumour / Bladder Cancer Flashcards

1
Q

What are the RF for renal cell carcinoma

A

Smoking
40+
Haemodyalysis
Von Hippellindau

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2
Q

What is Von Hippellindau

A

Aut Dom loss of tumour supressor gene
Px = Bilateral RCC -> Cysts and cerebellum cancers

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3
Q

What is the main triad of symptoms typical of RCC

A

Flank pain
Haematuria
Abdo mass
(May have varicocele)

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4
Q

What is the 1st line investigation for RCC

A

USS

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5
Q

What is the gold standard investigation for RCC

A

CT CAP

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6
Q

What is the staging used in RCC

A

Robson 1-4

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7
Q

How can RCC be treated

A

Nephrectomy
-Partial for bilateral RCC

If MET = Biologics/IFN-d

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8
Q

What is Wilm’s Tumour

A

Renal mesenchymal stem cell tumour in children

Nephroblastoma

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9
Q

What cells are affected in Wilm’s Tumour

A

Mesenchymal stem cells

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10
Q

What type of cancer is bladder cancer

A

Transitional cell carcinoma of bladder

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11
Q

What type of epithelium lines the bladder

A

Transitional epithelium/Urothelium

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12
Q

What are the risk factors for TCT/Bladder cancer

A

THINK MALE PAINTING SMOKER
-Especially 2-Naphtylamine

Chemo and Radio

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13
Q

What is the main sign of bladder cancer

A

Painless haematuria

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14
Q

How can TCC/Bladder cancer be diagnosed

A

Flexible Cystoscopy w/ Biopsy

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15
Q

How can TCC/bladder cancer be managed

A

TURBT/Cystectomy
Chemo
Palliative

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16
Q

If a patient has schistomiasis, what cancer are they most likely to have

A

Squamous cell carcinoma>TCT

17
Q

What is the most common GU cancer

A

Renal cell Carcinoma in 40+

18
Q

What is the prevalence of TCC, SCC and Adenocarcinoma

A

Transitional = MC
Squamous
Adenocarcinoma = LC

19
Q

What is Wim’s tumour also known as

A

Nephroblastoma

20
Q

What paraneoplastic syndrome presents in Renal cell carcinoma

A

Stauffer syndrome
Px = chloestasis and hepatosplenomegaly
2nd to raised IL6

21
Q

What is the histology of Renal cell carcinoma

A

Clear cells

22
Q

What is Wilm’s tumour associcated with

A

Bechwith-Wiederman
Px = macroglossia, macrosomia and neonatal hyperglycemia

GU (10 decks)

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