Renal Cancer NM Flashcards

1
Q

RCC T

A
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2
Q

RCC N

A

Renal hilar
Caval
Aortic LN

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3
Q

RCC M

A

Lung
Bone - - lytic
Liver
Adrenal
17% present with MTS

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4
Q

RCC paraneoplastic

A

Hypertension
Polycythemia
Hepatic dysfunction (Stauffer sy)
Amyloidosis
Neuromyopathy, Cushing, galactorrhea

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5
Q

RCC risk

A

Von Hippel Landau
Tuberous Sclerosis
Hereditary leiomyomatosis 17% type 2 papillary RCC
Sickle cell trait rare renal medullary ca, poor prognosis, MTS
Birt-Hogg-Dube chromophobe RCC

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6
Q

Von Hippel Landau

A

24-45% RCC clear cell bilateral
Pancreatic cyst and NET
Pheo
Retinal angioma

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7
Q

Tuberous Sclerosis

A

2-4% clear cell RCC
34-80% angiomyolipoma - - India ink artifact
CNS, thoracic, derma findings

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8
Q

RCC type

A

Clear cell 65-80% - arterial enhancement, high T2
Papillary 10-15% - slow enhancement, low T2
Chromophobe 4-11% - middle enhancement, intermediate T2, central scar

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9
Q

Radical nephrectomy

A

T1-2 GFR >45
Kidney, adrenal, peri renal fat, fascia Gerota, LN
<3 cm lesion - - thermal ablation

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10
Q

T3 treatment RCC

A

Radical resection, EBRT, arterial embolization

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11
Q

Most avid FDG

A

Papillary type 2 RCC esp in case of hereditary leiomyomatosis and RCC syndrome
Main indication - - RCC resectable with solitary MTS

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12
Q

TCC of Upper tract M

A

Liver
Lung
Bone
GIT
Peritoneum

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13
Q

TCC of Upper tract risk

A

Smoking
Coffee >7 cups a day
Cyclophosphamide chemotherapy
Balkan nephropathy
Horseshoe kidney

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14
Q

TCC of Bladder T

A
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15
Q

TCC of Bladder N3

A

Common iliac LN

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16
Q

TCC of Bladder M

A

Liver
Lung
Bone (lytic pelvis, spine)
Peritoneum

17
Q

Recurrent TCC risk

A

Deep bladder wall invasion
Tumor >3 cm
Multiple lesions
Hydronephrosis
Lamina propria invasion
Prostate involvement

18
Q

Urethral carcinoma T4

A

Bladder wall invasion
Stage IV

19
Q

Fluorothymidine = F-FLT

A

Cell proliferation marker
Correlated with Ki67
Predict more aggressive RCC

20
Q

F-Fluoride

A

More sensitive than bone scan in lytic MTS

21
Q

F-FMISO

A

Assessment of tissue hypoxia
Modest uptake in RCC, not predictive of response to therapy

22
Q

C tracers for Bladder cancer

A

No urinary excretion
Choline - cell proliferation, no uptake in premalignant lesion or small non invasive tumor
Methionine - amino acid transport, peak uptake at 10 min
Acetate - similar accuracy as MRI and CT

23
Q

RCC stage III

A

N1

24
Q

Renal pelvis SCC

A

Ass with xanthogranulomatous pyelonephritis

25
Q
A

RCC

26
Q

Bladder cancer risk

A

Smoking
Industrial carcinogens
Arsenic in water
Recurrent UTI and stones
Shistosoma hematobium

27
Q

Renal angiomyolipoma

A

Involve cortex
Macroscopic fat content HU <-20
Similar to simple cyst
TS - - multiple