Ped NM Flashcards
PET
Radiation burden reduce 50%
2.5 MBq/kg
0.2 mg/kg fusid to increase urine extraction
CT
Dose length product converted into effective dose values
Pitch >1
Slice increment = slice thickness, no overlap
Activate dose modulation system
SPECT/CT
Reduce scan length
Can rule out malignant bone lesions
Evaluate soft tissue involvement
Bone scan radiation dose
<3 mSv
F-fluoride PET
Better spatial resolution
Shorter duration of study (max 90 min)
Condylar hyperplasia
Asymmetric growth of mandibular condylar metaphysis
Time for surgery at the end of developing age growth, before arising of degenerative alteration
Bone scan reveal when metabolic activity of metaphysis is declining compared to reference bone
Dynamic renal scan
Tc-MAG3 and Tc-EC
Greater renal extraction - - better visualisation
15-20s/frame for 30-45 min posterior
Static after upright position
Congenital Hydronephrosis
Self-limiting condition without obstruction
Kidney damage - - pyeloureteroplasty
Static renal scan
Pinhole collimator
Postinfection scar - cold defect, triangular
At least 6 months after UTI
Negative scan - - absent or very low reflux - - no need for MCUG
Confirm/Exclude acute pyelonephritis
Cystography
Intravesical administration of Tc
Most sensitive for VUR
Recurrent UTI - - detect and quantify VUR
MCUG is better for first evaluation
#6 French no balloon catheter warm saline mixed with Tc-pert or Tc-SC 15-30 MBq - - bladder max capacity - - remove catheter - - void
Follow up VUR or first exam when bladder dysfunction and urethral anomalies excluded
Cystography protocol
10s/frame filling phase
2-5s/frame voiding phase
Tracer in ureter and renal pelvis - - VUR
Thyroid
Tc-pert or I123-iodide
I131-high radiation burden
Uptake 0.4 MBq
4-6-24-96 h
Thyroid cancer
Secondary after radiotherapy of HL, neuroblastoma - DTC
Primary cancer infiltrates capsule more often than adult - - T3
I131 cumulative activity <18.5 GBq to avoid sialoadenitis
After surgery – radioiodide ablation
Neuroblastoma
Most common extracranial solid tumor of childhood
Adrenal or retroperitoneum
Diagnosed after 1 year - - advanced disease and worse prognosis
I123-MIBG
Diagnostic
Better image quality and lower radiation
159 keV, no beta
T1/2 13h
I131-MIBG
Target therapy
364 keV, beta
T1/2 8 days
Theragnostic