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NM By Myself > Bone Tumor NM + pictures > Flashcards

Bone Tumor NM + pictures Flashcards

1
Q

Osteosarcoma

A

painful mass rising at metaphyseal regions
most common knee (the end of long bones)
Conventional type 80% – 10-20 years
Parosteal sarcoma – posterior distal metaphysis of femur

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2
Q

Osteosarcoma T

A

T1 < 8 cm long
T2 > 8 cm long
T3 2 lesions in one bone

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3
Q

Osteosarcoma risk

A

Polyostotic Paget long term – secondary
Previous radio
Familial retinoblastoma
Rothmund-Thomson sy (skin)
Bone infarct

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4
Q

Osteosarcoma M

A

lung
bone
LN

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5
Q

Osteosarcoma X-ray

A

Medullary and cortical bone destruction, wide zone of transition (permeative or moth-eaten appearance), aggressive periosteal reaction

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6
Q

Osteosarcoma CT

A

Staging, lytic lesions
Chest – MTS
Osteoid matrix – cloud like, poorly defined
Cartilage matrix – dots, rings, arcs of calcification <2mm

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7
Q

Osteosarcoma MRI

A

Joint-to-joint
Assessment of growth plate – 75-88% cross growth plate to epiphysis

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8
Q

Osteosarcoma NM

A

Bone scan: 3-phase positive, extent of osseous diffusion, level of bone resection
FDG: high grade intense uptake – tumor-to-background ratio cutoff 3.0 for malignant lesion
Tl, MIBI, Fluoride
SUV <2 after therapy – good response
SUV >5 – poor response

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9
Q

Osteosarcoma therapy

A

Effective neoadjuvant – less amputation – active ossification mimics therapy failure – SUV <2.5 post therapy predicts tumor necrosis
Enlarge on posttherapy image

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10
Q

Osteoid osteoma

A

Benign
Pain at night
Cortex of long bones (50% femur or tibia)
Intracortical <2cm nidus + mineralization, cortical thickening, reactive sclerosis

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11
Q

Osteoblastoma

A

Benign
Posterior element of spine (cervical)
Nidus >2cm
Greater potential for growth, bone destruction, malignant transformation, recurs

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12
Q

OO NM

A

Bone scan: lucent nidus surrounded by sclerosis – very hot spot + surrounding diffuse mildly increased uptake
SPECT - “one stop shop”
FDG – response to treatment

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13
Q

Ewing Sarcoma

A

4-15 years
Pretreatment high SUV – high grade
SUV >5.8 – poor prognosis
Post-neoadjuvant SUV <2.5 – good response (90% necrosis)

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14
Q

Ewing sarcoma Prognostic factor

A

size of lesion and distant MTS

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15
Q

Ewing Sarcoma NM

A

diaphysis of long bone (femur)
Bone scan: nonspecific increased uptake
FDG: >MRI in skip lesions, MTS LN
< chest CT

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16
Q

Chondroma

A

Benign, 30-80 years
Compose of mature hyaline cartilage – limited growth potential, not aggressive

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17
Q

Enchondroma

A

occur in medullary canal
melting sore at pressure
20-30 years
>6cm – high risk for chondrosarcoma

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18
Q

Risk for chondrosarcoma

A

Ollier disease
Mafucci disease
Exostosis
Most likely to seed biopsy track

19
Q

Chondroma CT

A

Cartilaginous matrix, endosteal scalloping
Thickness of cap >2cm – malignant

20
Q

Chondroma NM

A

Bone scan: cartilage matrix with increased uptake – malignant
FDG: low SUV for benign
SUV >2 threshold for malignant
No radio, no chemo

21
Q
A

Osteoid osteoma

22
Q
A

Osteosarcoma

23
Q
A

Chondrosarcoma

24
Q
A

Ewing sarcoma

25
Q
A

Enchondroma

26
Q
A

Chondroma

27
Q
A

Osteosarcoma

28
Q
A

Chondrosarcoma

29
Q
A

Fibrous dysplasia

30
Q
A

MTS superscan

31
Q
A

Hypertrophic pulmonary osteoarthropathy

32
Q
A

Spondylodiscitis

33
Q
A

Honda sign
Sacral insufficiency fracture

34
Q
A

Chicken bone
Osteomalacia

35
Q
A

Uptake in lung and stomach
Hyperpara

36
Q
A

Metabolic superscan

37
Q
A

Grenadier soldier
Hyperpara

38
Q
A

Rosary beads
Hyperpara

39
Q
A

Brown tumor in Hyperpara

40
Q
A

Shin splints

41
Q
A

Stress fracture

42
Q
A

AVN

43
Q
A

CRPS

44
Q
A

Paget

NM By Myself (25 decks)

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