renal Flashcards

1
Q

HUS symptoms

A

thrombocytopenia, anemia, and acute renal failure

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2
Q

treatment for HUS

A

dialysis

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3
Q

Electron microscope findings of acute poststreptococcal glomerulonephritis

A

subepithelial humps from immune complex deposition

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4
Q

poststreptococcal glomerulonephritis presentation

A

young child with dark urine, periorbital edema, proteinuria

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5
Q

lab findings poststreptococcal glomerulonephritis

A

positive antistreptolysin o titer, RBC casts in urine, decreased levels of complement

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6
Q

what type of hypersensitivity reaction is poststreptococcal glomerulonephritits

A

type III

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7
Q

EM findings of membranoproliferative glomerulonephritis

A

subendothelial immune complex deposition (C3 and IgG)

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8
Q

IF findings of membranoproliferative glomerulonephritis

A

granular appearing from immune complexes

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9
Q

H & E stain of membranoproliferative glomerulonephritis

A

tram-track appearance due to splitting of the basement memrane with mesangial proliferation

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10
Q

differentiation between type 1 and 2 of membranoproliferative glomerulonephritis

A

type II membranoproliferative glomerulonephritis will have the presence of C3 nephritic factor leading to dense deposit disease

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11
Q

what does C3 nephritic factor do?

A

stabilizes C3 convertase so type II membranoproliferative glomerulonephritis pts will have low C3 levels

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