endocrine

Question 1

MEN syndrome inheritance pattern

Answer 1

autosomal dominant, RET protoncogene (MEN2)

Question 2

MENIIA syndrome

Answer 2

medullary thyroid cancer, pheochromocytoma, parathyroid hyperplasia

Question 3

MENIIB syndrome

Answer 3

medullary thyroid cancer, pheochromocytoma, oral and intestinal ganglioneuromas, marfanoid habitus

Question 4

MENI

Answer 4

parathyroid (hyperplasia/tumor), pituitary (prolactinoma/GH), pancreatic (gastrinoma/VIPoma/insulinoma)

Question 5

Treatment for pheochromocytoma

Answer 5

alpha blockers, THEN beta blockers + surgical removal

Question 6

Rule of 10’s

Answer 6

Pheochromocytoma: 10% bilateral, 10% in children, 10% malignant, 10% extra adrenal

Question 7

FSH receptor

Answer 7

Gs: cAMP 2nd messenger

Question 8

GsCPR: cAMP as 2nd messengers

Answer 8

FLATChAMP: FSH, LH, ACTH, CRH, hCG, ADH (V2), MSH, PTH, calcitonin, GHRH, glucagon

Question 9

cGMP as 2nd messengers

Answer 9

NO, ANP, BNP

Question 10

IP3 as 2nd messenger

Answer 10

GOAT HAG: GnRH, Oxytocin, ADH (V1), TRH, Histamine (H1), Angiontensin II, Gastrin

Question 11

Receptor tyrosine kinase

Answer 11

GH, prolactin, G-CSF, EPO