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STEP > heme > Flashcards

heme Flashcards

1
Q

AML histologic finding

A

auer rods (especially in APL) in cytoplasm

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2
Q

AML + DIC dx?

A

acute promyelotic leukemia: M3 variant of AML

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3
Q

APL translocation

A

t (15;17)

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4
Q

treatment of AML (APL)

A

all-trans retinoic acid (vitamin A)

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5
Q

MOA of all-trans retinoic acid in APL

A

induces differentiation of neoplastic myelocytes

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6
Q

general findings seen in leukemias

A

infection (decreased WBCs), hemorrhage (decreased platelets), anemia (decreased RBCs)

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STEP (17 decks)

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