Renal 3 Paulson

Question 1

A ______ cyst has a thin wall without septa, calcifications or solid components

Answer 1

simple

Question 2

How to dx a simple cyst?

Answer 2

Ultrasound or CT

Question 3

A ______ cyst may have septa, calcifications, or solid components and are associated with increased risk of malignancy

Answer 3

complex cysts

Question 4

Inherited diseases that cause renal cyst development and progressive renal failure from continued enlargement of cysts

Answer 4

Polycystic Kidney Disease (PKD)

Question 5

Common clinical presentations of Polycystic Kidney Disease (PKD)

Answer 5

Hypertension, hematuria, proteinuria, flank pain, nephrolithiasis

Question 6

PKD can also cause extrarenal manifestations like

Answer 6

• Cerebral aneurysms

- cardiac valve disease

Question 7

How to dx Polycystic Kidney Disease (PKD) in most people?

Answer 7

U/S

Question 8

How to dx Polycystic Kidney Disease (PKD) in children?

Answer 8

genetic testing

Question 9

How to treat someone with PKD and HTN?

Answer 9

ACEI (prevents progression or renal disease and dec risk of CV mortality)

Question 10

PKD tx to help with BP?

Answer 10

Dietary sodium restriction <2

Question 11

PKD tx to help with heart disease?

Answer 11

statins

Question 12

For those 18-55 with GFR >25 and high risk for progression to ESRD what is the tx?

Answer 12

Tolvaptan (Samsca)

Question 13

This medication slows progression of PKD

Answer 13

Tolvaptan (Samsca)

Question 14

In someone taking Tolvaptan (Samsca), what should we make sure they also take with it?

Answer 14

Need to ensure adequate water intake

Question 15

What are some s/e of Tolvaptan (Samsca)?

Answer 15

inc LFTs and liver toxicity, polyuria, polydipsia, CP, HA

Question 16

This treatment for PDK suppresses ADH levels and inhibits cyst growth?

Answer 16

Increased fluid intake