Paulson Peds Nephro Flashcards

1
Q

What is the criteria for pediatric CKD?

A
  • GFR <60 for >3 months

- GFR >60 ml/min + evidence of structural damage

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2
Q

What is the mc cause of pediatric CKD?

A

Congenital disease

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3
Q

What are S/S of pediatric CKD (nonglomerular)?

A
  • Polyuria (large volumes dilute urine)
  • Elevated serum Cr
  • Poor growth
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4
Q

What are S/S of pediatric CKD (glomerular)?

A
  • Tea or cola colored urine
  • -> RBC casts
  • Edema
  • Elevated BP for age
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5
Q

Best imaging for peds kid with possible CKD?

A

U/S

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6
Q

Treatment for peds CKD?

A
  • Treat underlying cause
  • Prevent/slow progression
  • Treat complications
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7
Q

What med is preferred for kids with HTN and proteinuria?

A

ACEI/ARB

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8
Q

A difference between kids and adults with CKD is that in kids…

A

You don’t have to limit protein intake whereas in adults you should

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9
Q

What are three common symptoms of CKD?

A
  • Usually start around stage 3
  • -Anorexia
  • -Fatigue
  • -N/V
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10
Q

Once GFR <30, what should you do to treat peds patient with CKD?

A
  • Prepare the family
  • Kidney transplant
  • 2nd: peritoneal dialysis (in back)
  • 3rd: hemodialysis (fistula)
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11
Q

What is the difference between renal dysplasia and renal hypoplasia?

A

Renal dysplasia = malformed kidneys and they could have cysts (multicystic dysplasia)

Renal hypoplasia= small kidney (by 2 SD)

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12
Q

What is renal agenesis?

A

-missing a kidney and often ASYMPTOMATIC and found incidentally

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13
Q

What are signs and symptoms of renal dysplasia, hypoplasia or renal agenesis?

A

Kids that just dont look right

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14
Q

What imaging for renal dysplasia, hypoplasia or renal agenesis?

A

Renal u/s

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15
Q

Sclerosis (hardening) in parts of at least 1 glomerulous in the entire kidney biopsy specimen when examined histologically

A

focal segmental glomerulosclerosis

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16
Q

Acute onset of nephrotic syndrome is a finding of what condition?

  • Peripheral edema
  • Proteinuria
  • Hyopalbuminemia
A

focal segmental glomerulosclerosis

17
Q

Treatment for HTN + focal segmental glomerulosclerosis?

A

ACEI/ARB

18
Q

Treatment for focal segmental glomerulosclerosis + HLD?

A

Statin/niacin

19
Q

Pattern of glomerular injury on renal biopsy with characteristic changes on light microscopy

A

membranoproliferative glomerulonephritis

20
Q

membranoproliferative glomerulonephritis is similar to _____ in adults

A

AKI

21
Q

How to dx membranoproliferative glomerulonephritis?

A

Renal bx

22
Q

How to treat mild membranoproliferative glomerulonephritis?

A

ACEI/ARB

23
Q

How to dx severe membranoproliferative glomerulonephritis?

A

Cyclophosphamide or MMF + steroids or rituximab Immunosuppressants

24
Q

This is the most common cause of nephrotic syndrome in kids?

A

Minimal change disease

25
Q

If you see nephrotic syndrome in kids… think of what disease?

A

Minimal change disease

26
Q

What are the symptoms of Minimal change disease in kids?

A
  • Fluid in all the wrong spaces so dehydrated internally

- Tachycardia, oliguria, peripheral vasoconstriction, decreased GFR, elevation of renin, aldo and NE

27
Q

Treatment for Minimal change disease?

A

Prednisone

28
Q

Treatment for Minimal change disease if resistant to steroids?

A

Cyclophosphamide or rituximab

29
Q

The most common kidney fusion anaomaly that is the cause of various genetic components?

A

Horshoe kidney

30
Q

Those with a horseshoe kidney are at increased risk for a _________ tumor

A

Wilms tumor

31
Q

How to dx a horseshoe kidney?

A

U/S

32
Q

How to treat a horseshoe kidney?

A

Most do fine without intervention but if have VUR then consider prophylactic abx