Renal Flashcards
stimulates the bone marrow to make red blood cell
erythropoietin
regulates blood pressure
renin
the active form of vitamin D, which helps maintain calcium for bones and for normal chemical balance in the body
calcitriol
problems in the glomerulus
allow proteins and RBC to be filtered though the basement membrane into urine
problems in kidney tubules
allow abnormal excretion of H+ , CL- , Bicarb , Na+, K+
What are the standard serum indicators of renal function?
BUN and Cr
What is the most reliable single indicator of glomerular function?
Cr
What radiographic study would you use to evaluate a patient for polycystic kidney disease?
renal ultrasound
most common abdominal mass on newborn exam
large kidney
unilateral renal agenesis can be associated with
IDM, VACTERL, Turner’s
most common type of PKD
autosomal dominant
clinically mild or insignificant renal abnormalities
unilateral renal agenesis, horseshoe kidney, pelvic or ectopic kidneys
renal parenchymal abnormalities (problematic)
dysgenesis or PKD
bilateral renal agenesis
Potter’s
PKD presents in infancy
recessive
PKD associated with other cysts
dominant
PKD characterized by marked enlargement of both kidneys
recessive
Marked bilat renal enlargement. Interstitial fibrosis and tubular atrophy. Renal Failure early childhood
ARPKD
Typically present in middle adulthood.
Assoc with other cysts : hepatic, pancreatic, ovarian and cerebral aneurysm
ADPKD
most common cause of bladder outlet obstruction in males. Male infant with anuria or poor stream
posterior urethral valves
treatment posterior urethral valves
urgent surgical drainage necessary
Reflux of urine from bladder to ureter during bladder contraction, or back up from bladder (ie neurogenic bladder)
vesicoureteral reflux
complications vesicoureteral reflux
recurrent UTI, renal damage, HTN, CKD
VUR prophylaxis
nitro or bactrim
which grade of VUR should you consider surgically re-implanting the ureter
grade IV and up
Only occurs in males, account for 20% of all childhood end-stage renal failure
posterior urethral valves
this can be associated with posterior urethral valves. Can see cryptorchidism and absent abdominal musculature
Prune belly syndrome
dysplastic kidneys, dilated urinary tract, and malformed blasser
posterior urethral valves
hematuria- non glomerular
dysuria, associated back pain (pyelonephritis), colicky pain, bright red blood or clots
hematuria- glomerular (nephritis)
tea colored urine, smoky, RBC TNTC, +/-RBC casts, painless
most common cause of hematuria (gross or micro)
UTI
what makes you heavily suspect nephritis/nephropathy
proteinuria plus hematuria
common signs GN
high Cr, edema, HTN, hematuria
most common for of GN in childhood
acute post-streptococcal GN
History of culture + GAS , or +antistreptolysis O titer
Can have low complement (C3) levels
acute post-streptococcal GN
treatment acute post-strep GN
No specific treatment. Supportive. Antibiotics if GAS still present. Treat HTN