Immunodeficiency

Question 1

primary or secondary immune deficiency more common

Answer 1

secondary

Question 2

how are primary immunodef categorized

Answer 2

by defect

cellular, humoral, phagocytes, complement

Question 3

children with severe, prolonged, unusual recurrent infections

Answer 3

SPUR

Question 4

Unable to make specific antibodies

Multiple/severe bacterial infections and persistent upper RTI

Answer 4

b cell defect

Question 5

most common immunodeficiency

Answer 5

immunoglobulin/antibody (B cell defect)

Question 6

kids with opportunistic infections, persistent thrush, diarrhea, poor growth, FTT

Answer 6

T cell defects

Question 7

Profound lack of T-cell numbers or function and B-cell dysfunction resulting from absence of B cells from the gene defect itself or secondary to lack of T-cell function

Answer 7

SCID

Question 8

neutrophil disorders can be associated with

Answer 8

deficient cell numbers (low ANC)
deficient chemotaxis
deficient function

Question 9

kids show up with recurrent abscesses or poor wound healing or gingivitis or invasive fungal infections

Answer 9

neutrophil defects

Question 10

test for complement defects

Answer 10

CH50

Question 11

kid presents with recurrent bacterial infections, SLE like illness, recurrent meningococcal infections, autoimmunity, glomerulonephritis

Answer 11

complement defects