remainder of chapter 3

Question 1

gives rise to an mRNA that is never transcribed,

Answer 1

pseudogenes

Question 2

a large portion of the human genome has ______with other species

Answer 2

orthologous genes

Question 3

top down approach for mutagenic screening of heritable changes

Answer 3

classical genetic analysis

Question 4

bottom up approach for specific gene is altered and phenotypic result is examined

Answer 4

reverse genetics

Question 5

short RNAs that form a complex with mRNA which is then recognized and degraded

Answer 5

RNAi

Question 6

repetitive parts of the DNA in organisms other than humans can be used to target specific sequences

Answer 6

Transposons

Question 7

active in humans and give rise to mRNA

Answer 7

retrotranposons

Question 8

mutations in these genes cause changes in all circadian behaviors generated by the internal clock

Answer 8

period or per

Question 9

per is essential for

Answer 9

rhythmic behavior

Question 10

when are levels of PER the highest

Answer 10

after dusk and during the night

Question 11

when are levels of PER the lowest

Answer 11

early morning

Question 12

clock gene regulates two properties of circadian rhythm

Answer 12

the length of the circadian rhythm

persistence of rhythmic in the absence of sensory input

Question 13

mouse clock and fly per genes share a domain called the

Answer 13

PAS domain

Question 14

CLOCK is highest at what time of the day

Answer 14

middle of the day

Question 15

____activates ____transcription while ____represses _____function

Answer 15

CLOCK
PER
PER
CLOCK

Question 16

oscillation of circadian rhythm genes can be reset by what

Answer 16

light

Question 17

this gene encodes a signal transduction enzyme, a protein kinase activated by the cellular metabolite cyclic guanosine 3’-5’ monophosphate (cGMP)

Answer 17

for gene

Question 18

neuropeptides ____and ____ stimulate mammalian affiliation behaviors such as pair bonding and parental bonding with offspring

Answer 18

oxytocin and vasopressin

Question 19

in prarie vols V1a is expressed highly in which area of the brain

Answer 19

ventral pallidum

Question 20

in montane vols V1a is expressed highly in which part of the brain

Answer 20

lateral septum

Question 21

what gene is mutated in angelmans sydrome

Answer 21

ube3a

Question 22

angelmans syndrome is only derived from the

Answer 22

maternally derived chromosome (cannot get from father)

Question 23

when an mRNA is expressed from only one of the two autosome copies

Answer 23

parental imprinting

Question 24

prader-willi syndrome is only derived from the

Answer 24

paternally derived chromosome (cannot get from mother)

Question 25

mutation of DCX protein causes what

Answer 25

double cortex syndrome