Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Microbiology 3 > Regulation of Bacterial Gene expression > Flashcards

Regulation of Bacterial Gene expression Flashcards

exam 3

You may prefer our related Brainscape-certified flashcards:
Biology 101 flashcards
1
Q

in bacteria, multiple genes can be in the same transcription unit

A

operon

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

a sequence of DNA bases that is transcribed to give a single, discrete complementary RNA

A

transcription unit

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Toxin B and holin

A

operon

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

positive regulator

A

tcdR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

toxin B

A

tcdB

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

holin

A

tcdE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

ToxinA

A

tcdA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

negative regulator

A

tcd C

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

positive regulator, toxin B, holin, Toxin A, negative regulator

A

pathogenicity locus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

special region of DNA where RNA polymerase binds for the purpose of initiating transcription

A

Promoter site

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

a site within the DNA or RNA product at which RNA synthesis stops

A

Termination Site

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

two key elements of most promoters

A

-35 and -10

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

blocks elongation

A

rifamycins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

blocks initiation

A

lipiarmycins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

example of a lipiarmycins

A

fidaxomicin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

exampled of rifamycins

A

rifampicin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

inhibitors of RNA synthesis that bind to Beta subunit of RNA polymerase

A

Rifamycins and Lipiarmycins

18
Q

necessary for recognition of the promoter region of a gene

A

sigma subunit

19
Q

Release of ______ after initiation of transcription from ______

A

sigma subunit from the holoenzyme

20
Q

alpha-2-Beta-Betaprime-sigma

A

Holoenzyme

21
Q

alpha-2-Beta-Betaprime

A

Core enzyme

22
Q

There is one type of RNA polymerase _______ but many kinds of _______

A

There is one type of RNA polymerase core enzyme but many kinds of sigma-subunits

23
Q

Different ______- recognize promoters with different sequencces

A

sigma subunit

24
Q

encoded in the DNA sequence appearing as a region of dyad symmetry

A

Factor-independent termination

25
Q

binds directly to RNA pol and causes the polymerase to stop and release when reaching the factor-dependent termination

A

Rho factor

26
Q

receptor-dependent termination requires _____ for ______________

A

Rho factor for transcription termination

27
Q

positive regulator and binds upstream of the promoter

A

X

28
Q

negative regulator, a represor binding site that can overlap promoter or be downstream of the promoter

A

Y

29
Q

sigma factor for toxin gene transcription

A

TcdR

30
Q

antibiotic and toxin production in liquid medium

A

Stationary- tcdR

31
Q

tcdR is inactivated by ______ in the _______ phase

A

CodY-Ile is active in the exponential phase

32
Q

tcdR is expressed in the

A

stationary

33
Q

cody only works a repressor when

A

isoleucine is bound

34
Q

more isoleucine in the

A

exponential phase

35
Q

metabolic active phase

A

exponential

36
Q

CoDY is _____ in stationary phase

A

inactive

37
Q

CoDY is ______ in exponential phase

A

active

38
Q

tcdR in nutrient limitation

A

active and toxins synthesized

39
Q

anti sigma factor

A

tcdC

40
Q

tcdC binds to ____ and inactivates it

A

tcdR

41
Q

High toxin production:

a. Mutation in tcdC that inactivates the protein
b. Mutation in tcdR that inactivates the protein
c. Mutation in codY that inactivates the protein
d. Mutation in promoter of tcdB that inactivates the promoter

A

a. Mutation in tcdC that inactivates the protein

AND

c. Mutation in codY that inactivates the protein

Microbiology 3 (6 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions