Reflux Drugs Flashcards
1
Q
-prazole drugs
- Class
- MoA
- Indications
- Side effects
- Monitoring
- Extra info
A
Class:
Proton pump inhibitor
MoA:
Irreversible inhibitors of H+/K+ ATPase in gastric parietal cells.
Indications:
Reflux, helicobacter pylori
Side effects:
Gastrointestinal disturbance, hyponatremia, hypomagnesia, osteoporosis, vitamin B12 deficiency, gastric malignancy, C.difficile infection
Monitoring:
Check magnesium before initiation
Extra info:
Pro-drug. Can mask effects of gastric cancer. May make clopidogrel less effective.
