Red blood cells – basic characteristics. Hemolysis.

Question 1

red blood cells – basic characteristic 1

Answer 1

biconcave disc
- allows it to pass it narrow spaces like capillaries

Question 2

red blood cells – basic characteristic 2

Answer 2

anucleated
- large SA:V for gas exchange

Question 3

red blood cells – basic characteristic 3

Answer 3

size = 7mm

Question 4

red blood cells – basic characteristic 4

Answer 4

no mitochondria so rely on anaerobic respiration for ATP

Question 5

red blood cells – basic characteristic 5

Answer 5

hemoglobin proteins which binds to O2/CO2

Question 6

red blood cells – basic characteristic 6

Answer 6

LIFE CYCLE

erythropoiesis

Question 7

red blood cells – basic characteristic 7

Answer 7

functions x5

Question 8

hemolysis

LIST

Answer 8

definition
types
clinicals

Question 9

hemolysis - definition

Answer 9

RBC bursting releasing hemoglobin into the bloodstream

Question 10

hemolysis - type 1

Answer 10

INTRAVASCULAR HEMOLYSIS

• occurring within the blood cells

causes
- genetic conditions = spheryocytosis/ sickle cell/ thalassemia causes abnormalities in RBC membrane
- G6PD under oxidative stress

Question 11

hemolysis - type 2

Answer 11

EXTRAVASCULAR HEMOLYSIS

• occurring outside blood vessels

causes
- mechanical damage -> heart stents
- autoimmune diseases = hemolytic anemia
- malaria infections

Question 12

hemolysis - clinical 1

Answer 12

jaundice

too much hemoglobin breakdown = increase in bilirubun

Question 13

hemolysis - clinical 2

Answer 13

ANEMIA

too much hemoglobin breakdown = less iron transported by hemoglobin

Question 14

hemolysis - clinical 3

Answer 14

Hemoglobinuria

free Hb in urine