RECEPTORES Flashcards

1
Q

citocinas INFLAMATORIAS

A

IL1, IL6, TNF alpha

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2
Q

citocinas ANTIVIRALES

A

IFN alpha y beta

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3
Q

MEMBRANALES

A

TLR
CLR
SR
FPR

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4
Q

CITOPLASMÁTICOS

A

NLR
RLR
CDS

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5
Q

SOLUBLES

A

Pentraxinas -> activación del complemento vía clásica
CLR
ficolinas
colectinas (MBL, SPA y SPD) -> neutralización
anticuerpo
complemento

fagocitosis opsónica

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6
Q

TLR membrana externa

A

1, 2, _, 4, 5, 6

Myd 88
NF-κB

citocinas INFLAMATORIAS: IL1, IL6, TNF alpha

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7
Q

TLR membrana interna

A

_, _, 3, _, _, _, 7, 8, 9

TRIFF
IRF 3-7

citocinas ANTIVIRALES: IFN alpha y beta

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8
Q

SR

A

MARCO, SRAI y AII, CD36
*Marco es una señora de 36 años

fagocitosis no opsónica

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9
Q

CLR membranales

A
  • para manosa (CD 206)
  • para langherina (CD207)
  • DC-sign (CD 209)
  • dectinas 1 (beta-glucano) y 2

fagocitosis no opsónica

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10
Q

FPR

A

quimiotaxis

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11
Q

NLR

A

INFLAMACIÓN

  • clásica
    señalosoma
    NF-κB
    citocinas INFLAMATORIAS: IL1, IL6, TNF alpha
  • no clásica
    inflamosoma
    procaspasa
    ILB activo
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12
Q

RLR

A

TRIFF
IRF 3-7

citocinas ANTIVIRALES: IFN alpha y beta

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13
Q

CDS

A

VÍA STING
IRF 3-7

citocinas ANTIVIRALES: IFN alpha y beta

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14
Q

TLR1

A

lipopéptido BACTERIANO

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15
Q

TLR2

A
  • peptidoglucano BACTERIANO
  • lipofosfatidilserina y lipoproteínas diacetiladas de HELMINTOS
  • fosfolipomanano de HONGOS
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16
Q

TLR4

A
  • LPS bacteriano gram-
  • glucoronoxido manano
  • glucolípidos de protozoarios y helmintos
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17
Q

TLR5

A

flagelina BACTERIANA

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18
Q

TLR6

A

lipopéptido BACTERIANO

19
Q

Dectina 1

A

Beta-glucano: Candida como LEVADURA

20
Q

Dectina 2

A

Candida como hifa

21
Q

CD 206

A

manosa y fucosa de HONGOS y BACTERIAS

22
Q

CD 207

A

Langherina manosa de HIFAS

23
Q

CD 209

A

manosa y fucosa

24
Q

SR

A

ácido lipoteicocico de BACTERIAS gram +

25
Q

TLR 3

A

ARNbc de VIRUS

26
Q

TLR 7

A

ARNmc de VIRUS

27
Q

TLR 8

A

ARNmc de VIRUS

28
Q

TLR9

A

ADN CpG de VIRUS, BACTERIAS y HONGOS

29
Q

NOD 1

A

peptidoglicano gram -

30
Q

NOD 2

A

peptidoglicano

31
Q

NLRP

A

DAMP

32
Q

RIG

A

ADN VIRAL

33
Q

CDS

A

ADN VIRAL

34
Q

CR1

A

C3b

35
Q

pentraxinas

A

fosfolípidos y fosfoazúcares de HELMINTOS

36
Q

FcγR1

A

IgG

37
Q

reconocimiento de BACTERIAS EXTRACELULARES

A

TLR 1, 2, 4, 5, 6, SR, complemento, anticuerpos, CD206, MBL, SPA, SPD, ficolinas H y L, FPR

38
Q

reconocimiento de BACTERIAS INTRACELULARES

A

TLR9, NOD 1, NOD 2, NLRP, CDS

39
Q

reconocimiento de HONGOS INTRACELULARES (levaduras)

A

Dectina 1, TLR9, NLR, CDS

40
Q

reconocimiento de HONGOS EXTRACELULARES (hifas)

A

TLR2, TLR4, Dectina 2, CD 206, CD 207, CD 209, SPA, MBL, complemento

41
Q

reconocimiento de VIRUS

A

TLR 3, 6, 7, 8, 9, RIG y CDS

42
Q

reconocimiento de PROTOZOARIOS

A

TLR2, TLR4, CDS

43
Q

reconocimiento de HELMINTOS

A

TLR 2, TLR 6, pentraxinas