Reading 1: Intro 3-18 Flashcards

1
Q

Name the 6 General Lab outcomes

A
  1. Calibrate and operate scientific equipment by following detailed lab manual
  2. Obtain informed consent from subject prior to exp
  3. Conduct physiology exp while recording experimental observation in notebook. Identify potential sources of error in scientific exp
    4.
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2
Q

Characteristics of a Good Lab Course

A
  1. Lab environment should be perceived as attractive by students
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3
Q

Purpose of BPK 407 Project

A

Gain experience conducting human physiology exp

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4
Q

What week do u submit project proposal that briefly outlines purpose of project

A

Week 8

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5
Q

What week to present exp and findings to other student

A

Week 13

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6
Q

How is the project report structured

A

Scientific journal article, 4-6 pages length, Times new roman 12 point font

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7
Q

What is the purpose of the abstract (200-250 words)

A

Provide short summary of article so reader can determine if should read entire article

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8
Q

Purpose of intro (2-3 paragraphs)

A

”- Provide reader w/info regrading WHAT physiologic question being answered, WHY important to answer”

  • Summarize theoretical background to the question
  • Explain why problem interesting
  • Summarize project n explain HOW it answers question
  • State hypothesis
  • Explain how hypothesis verify/support physiologic concept in question
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9
Q

Purpose of procedure (2-4 paragraphs)

A

”- Describe exactly how exp conducted”

  • Sufficient detail so as to replicate exp
  • Describe subjects used
  • List make n model of equipment
  • Describe detailed procedures followed
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10
Q

What is the purpose of results (2-4 paragraphs, tables, point form can be used)

A
  • Present results from exp
  • Use tables where appropriate
  • Use graphs where appropriate
  • Inc statistical analysis performed
  • Explain significance of results
  • Explain if hypothesis supported by results
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11
Q

What is purpose of discussion (2-3 paragraphs)

A

“-Compare results to other similar studies, n to recommend further research that’ll help u answer proposed q”

  • Discuss whether u obtained results u expected
  • Explain unexpected results
  • Is further research required to support hypothesis?
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12
Q

Purpose of conclusion (1 paragraph)

A
  • Summarize exp, briefly describe how results helped solve research q proposed
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13
Q

References (min 5 max 10)

A
  • Use APA style for all references and in-text citations
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14
Q

Purpose of 407 project PRESENTATION (20-25 min)

A

Gain experience presenting research findings to audience

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15
Q

What is the presentation graded on

A

Quality n effectiveness

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16
Q

How much is presentation worth

A

10% grade

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17
Q

What is the structure of the project proposal submitted in week 8

A
  • Clear n concise, summarizes hypothesis n methods used

- 3-6 double spaced pages in length

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18
Q

How many labs and lab reports performed in course

A

8 labs 8 reports

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19
Q

In ur lab report, what are the 9 different headings required?

A
  1. Raw data and observations made during lab
  2. Title and date (this begins formal report)
  3. Procedures
  4. Results
  5. Discussion
  6. Sources of error
  7. Questions
  8. Citations
  9. References
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20
Q

What is the late penalty? When is the last day reports will be accepted?

A

5% a day, no longer accepted after one week

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21
Q

What kind of abbreviations are accepted?

A
  1. SI units like kg for kilogram

2. If defined first e.g. electrocardiograph (ECG)

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22
Q

Past tense or present tense

A

Past

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23
Q

Is the word “significant” acceptable? If not, what instead?

A

No, use “dramatic” or “substantial”

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24
Q

What happens when u miss a lab session where there’s a required lab report

A

u get 0 for that lap report

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25
Q

What do tables need to have

A
  1. Title
  2. Headings for each column
  3. Units
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26
Q

What do graphs need to have

A
  1. Title
  2. Labelled axes
  3. Units
  4. Error bars
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27
Q

What indicates the accuracy of a measurement

A

of significant digits

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28
Q

8V implies how many significant digits and what is the actual output

A
  • 1 significant digit

- output btwn 7.5-8.5V

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29
Q

With sums and differences, how is the number of decimal places determined?

A

The # w/the least number of digits following the decimal point determines it

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30
Q

2997 + 104.6 + 0.135 = 3101.735… how many decimal places roundoff

A

3101.735 -> 3101

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31
Q

With products and quotients how much significant digits in result?

A
  • Equal that in the component measurements with least # of significant digits e.g. 6 mm / 25 mm/s = 0.24 -> round to 0.2s or 2x10^-1 ms
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32
Q

What are errors in this context

A

Degree of uncertainty associated w/all experimental measurements.

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33
Q

What do random errors cause

A

The result to spread in both directions/cluster about the true value

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34
Q

What do systemic errors cause?

A

Causes measured values to be consistently greater than or lower than true value. Also causes variability in measured value

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35
Q

What are random errors caused by

A
  • Variation in quantity being measured e.g. calf girth changes w/posture
  • Variation in measurement location
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36
Q

Example of how systemic errors made

A

Meter stick might be divided into 100 equal divisions but 101 ong so length of objects measured w/stick consistently overestimated by 1%

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37
Q

What are paradox errors

A

Occurs when position of needle on scale is read incorrectly e.g. from one side, resulting in systemic error
e.g. needle at 5cm read straight on correctly vs. needle read from side resulting in read as 4cm

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38
Q

Is it appropriate to add two or more independent errors? Why or why not?

A

No, causes overestimation of error cause addition presumes 2 errors will b maximal and in same direction simultaneously

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39
Q

What is the combined error formula (for 2 or more independent errors in single measurement)?

A

E = square root (E1^2 + E2^2 + … En^2)

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40
Q

What is the result of the combined error? Less or more than sum?

A

Greater than separate errors but less than their sum

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41
Q

How are dependent errors different from independent?

A

When error from one source affects error from another source, errors are dependent

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42
Q

Eqn to combine errors in calculations (sum and differences) when using values obtained from other measurements to derive other values

A

ΔX = square root ( (ΔA)^2 + (ΔB)^2+ (ΔC)^2 + (ΔD)^2 )

  • A and B are values obtained by measurement
  • X is derived value
  • DA and DB and DX are actual errors associated with A, B, and X respectively
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43
Q

Calculate error for calorimeter if A= 20 degrees, B=24 degrees, DA= 0.2, DB= 0.2,
X = B - A

A
X = 24-20 = 4
ΔX = sqrt ( ΔA^2 + ΔB^2)
ΔX = sqrt (0.2^2 + 0.2^2)
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44
Q

For errors involving products and ratios combining calculations, what is the eqn

A

ΔX / X = sqrt ( [ΔA/A]^2 + [ΔB/B]^2

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45
Q
What is DX if 
A= 100m
B = 5s
ΔA = 1m
ΔB = 0.2s
X = 100m / 5s = 20 m/s
A

ΔX/X = sqrt ( (ΔA/A)^2 + (ΔB/B)^2 )
ΔX/ 20m/s = sqrt (1m/s / 100m/s)^2 + (0.2s/5s)^2
ΔX = 0.8 m/s
Velocity is 20m/s +/- 0.8 m/s

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46
Q

How many sig figs are errors presented to?

A

1 sig fig

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47
Q

Equation for powers e.g. if X (derived value) = A^n where A is obtained from measurement

A

ΔX = Xn(ΔA/A)

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48
Q

What is biometrics

A

Branch of science that includes measurement of physiological variables n parameters

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49
Q

In the design or specification of medical instrumentation systems, what factors should be considered?

A
  1. Range
  2. Sensitivity
  3. Linearity
  4. Hysteresis
  5. Frequency Response
  6. Accuracy
  7. Signal to Noise Ratio
  8. Stability
50
Q

What is the range of an instrument

A

All lvls of input amplitude and frequency over which the device is expected to operate

51
Q

What is the sensitivity of an instrument

A

Determines how small a variation of a variable/parameter can be reliably measured
- results in nonlinearities or instability

52
Q

What is the linearity of an instrument

A

Degree to which variations in output of instrument follow input variations
- in linear system sensitivity would be same for all absolute lvls of input, whether high, middle, or low portion of range

53
Q

What is the hysteresis of an instrument

A

When a given value of measured variable results in different reading when reached in an ascending direction from that obtained when it is reached in a descending direction

54
Q

What can cause hysteresis

A

Mechanical friction

55
Q

What is the frequency response of an instrument

A

Its variation in sensitivity over the frequency range of measurement

56
Q

What is the term when an instrument system responds rapidly enough to reproduce all frequency components of the waveform w/equal sensitivity

A

Flat response

57
Q

What is accuracy

A

Measure of systemic error

58
Q

What are the 6 errors to be considered

A
  1. Errors due to tolerances of electronic components
  2. Mechanical errors in meter movements
  3. Component errors due to drift or temp variation
  4. Errors due to poor frequency reponse
  5. Errors due to change in atmospheric pressure or temp
  6. Reading errors due to parallax, inadequate illumination, or excessively wide ink traces on pen recording
  7. Zeroing of instrument
  8. Effect of instrument on parameter to be measured n vice versa
59
Q

Signal to noise ratio should be as ____ as possible

A

High

60
Q

Interference due to electromagnetic, electrostatic, or diathermy equipment is likely due to ___

A

poor grounding

61
Q

How does thermal noise and interference differ

A

Thermal noise limiting factor in detection of signals in other fields of electronics vs. interference is problem in biomedical system

62
Q

What is stability

A

Ability of system to resume steady-state condition following disturbance at input rather than be driven to uncontrollable oscillation

63
Q

What is baseline stability

A

Maintenance of constant baseline value w/out drift

64
Q

Give an example of a common DC voltage source and an example of an AC voltage source

A
  • DC: a cell/battery

- AC: wall outlet

65
Q

List several materials which have a high resistance to electric current flow

A

Rubber, glass

66
Q

List several materials which have a low resistance to electric current flow

A

Copper, silver

67
Q

What is the relevance of this info to the recommended rescue procedure for a victim who has been electrocuted by a broken power line falling on him/her

A

Wearing rubber soles can protect you from being electrocuted cause high resistance so current hard to flow

68
Q

Explain how adding a resistor to a parallel circuit inc current which flows thru that circuit

A

Adding individual resistors dec total resistance. Since current = voltage/resistance, dec resistance means inc current flow. Adding resistor path draws current so total current inc beyond capacity of fuse. Fuse blew to protect circuit from excess current causing overheated wires and house fire

69
Q

What is the purpose of amplifying biological signals? Is it desirable to have high gain or low gain on a biological amplifier?

A
  • enlarge signals that are normally hard to detect like skeletal muscle contractions
    High gain which means giving greater amplification to an input signal
70
Q

Why is it dangerous to touch internal components of an electrical instrument even when instrument powered off?

A

Some capacitor can be charged to extremely high voltages. If current flow thru you, u can be electrocuted

71
Q

What is AC

A

current that reverses its direction of flow

72
Q

What is a wall outlet

A

Ac voltage sources

73
Q

What is resistance

A

Limits or controls flow of current

74
Q

What is resistance and its units

A
  • Limits or controls flow of current

- Ohms

75
Q

What are good conductors and give example

A

Give up electrons more easily than atoms of other material and offer less resistance to current flow e.g. copper

76
Q

What is ohms law

A

Current in a circuit (I) = Voltage applied to a circuit (V) / resistance of a circuit (R)

77
Q

What is a simple device used to determine whether or not current is flowing thru a circuit

A

Lamp

78
Q

What are switches

A

Used to control when a circuit is closed (complete) or open. Current flows when switch is closed

79
Q

What are switches

A

Used to control when a circuit is closed (complete) or open. Current flows when switch is closed

80
Q

When devices r connected like knots in string this is called

A

Series

81
Q

What happens when 2 lamps connected in series w/voltage source and one lamp removed or burnt

A

other lamp will not light cause circuit not complete

82
Q

What is the total resistance in a series circuit equal to

A

Sum of resistance of each of its parts

83
Q

What is the total resistance in a series circuit equal to

A

Sum of resistance of each of its parts

84
Q

What is total resistance in parallel

A

1/total resistance = sum of inverse of each of all the individual resistances
1/RT = 1/5 + 1/3 = 8/15 –> RT = 15/8 = 1.9 ohm

85
Q

What is total resistance in parallel

A

1/total resistance = sum of inverse of each of all the individual resistances
1/RT = 1/5 + 1/3 = 8/15 –> RT = 15/8 = 1.9 ohm

86
Q

Why does adding individual resistances in parallel circuit dec total resistance

A

Total resistance in parallel circuit less than smallest of individual resistances

87
Q

Why does adding individual resistances in parallel circuit dec total resistance

A

Total resistance in parallel circuit less than smallest of individual resistances

88
Q

What is eqn for gain

A

gain = output voltage/input voltage

89
Q

What is a capacitor (aka condensor)

A
  • device which controls electricity by regulating flow of AC current
  • stores electrical charge
90
Q

What is capacitance and units?

A
  • Opposes any change in current

- Farads (C)

91
Q

How is a capacitor made

A

Sandwich insulating material e.g. glass between 2 conductors (metal plates)

92
Q

How is a capacitor charged

A

When voltage across capacitor reaches same potential as that of the cell, current stops flowing in this circuit

93
Q

How can a capacitor be discharged

A

By providing path for electrons to return to positive plate

94
Q

What does it mean when electric circuits are grounded

A

Pathway provided for electrons to flow into earth or ground

95
Q

Define ground

A

q

96
Q

Why is it dangerous to use monitoring instruments which have a 2-prong plug rather than a 3-prong plug

A

q

97
Q

Describe effects of 60 Hz electrical shock on heart muscle

A

In case of electric shock, current density thru heart reaches critical rang, and desynchronization process occurs sending heart into ventricular fibrillation

98
Q

Define “let-go current”

A

If victim comes into contact w/power source thru gripping, 9-20ma is distressing, cause he can’t “let-go” due to the skeletal muscle contractions

99
Q

With 60 Hz current in range of 50 milliamps to 3 amps can cause ventricular fibrillation. Defibrillation machines produce currents in the 6 to 10 amp range. Why can these higher currents reverse ventricular fibrillation rather than cause it?

A

W/high currents, all ventricular muscle fibres depolarize at once producing sustained contraction of whole organ, and then when shock removed, normal HR can resume

100
Q

Defines Ohms law and differentiate btwn series circuits n parallel circuits

A

I = V/ R or V = IR or Voltage = current x resistance
Current is the movement of electrons.
Voltage is the force which causes current to flow.
Resistance limits or controls the flow of current.

101
Q

What is leakage current n why is it dangerous

A

Series: devices are connected like knots in a string. If 2 lamps are connected in series w/a voltage source, the same current flows thru both of one and if one lamp removed or burnt out the other bulb won’t light as circuit is not complete
Parallel: open switches will disconnect 2nd land but the 1st lamp will still be lighted as there’s a complete circuit flowing thru it

102
Q

If u were in charge of EMG lab, what precautions would u take to ensure electrical safety of patients being tested

A
  1. Make sure subject wearing electrode out of reach of electrically operated devices or metallic conductors
  2. Integrity of ground system regularlly checked
  3. Avoid storing flammable liquids near electrical equipment
103
Q

Explain “the victim is capacitively coupled to power source”

A

aa

104
Q

Why is it good idea not to handle electrical equipment when standing on wet floor

A

V=IR, when skin wet, ur skin resistance will be much lower than normal thus given voltage will drive much more current into ur body

105
Q

Define electrode wrspt human physiology recordings

A

A type of transducer which changes ionic current into electric current

106
Q

What underlies myocardial DEfibrillation

A

Passing of high currents e.g. 6 amps thru the heart. W/high currents all the ventricular muscle fibers will be depolarized at once producing sustained contraction of whole organ, then when shock removed, normal HR resumes

107
Q

What is the most common form of leakage current

A

60 Hz

108
Q

Effect of 6-10 amps

A

Extreme heating effects, bruns

109
Q

50 ma-2.5 amps

A

Lethal zone (can cause heart to produce fibrillations)

110
Q

20 ma

A

Fainting, muscle paralysis

111
Q

10 ma

A

painful to most

112
Q

5 ma

A

one present standard of max safe current lvl

113
Q

1 ma

A

avg min threshold to pain

114
Q

500 ua

A

threshold of feeling - perceived as tingling

115
Q

How can victim receive electric shock

A
  1. Interposing oneself in path of current in series

2. Capacitively coupled to power source

116
Q

What are some factors to DECREASE resistance

A

Wetting skin, cleansing it, enlarging contact area, apply electrolytes

117
Q

What are some factors to DECREASE resistance

A

Wetting skin, cleansing it, enlarging contact area, apply electrolytes

118
Q

What are 6 prevention measures to insure integrity of ground system in room

A
  1. Check all 3 wire plugs, repair broken insulation
  2. Dispose 2 wire cord or polarize them so that neutral is continuous in all outlets
  3. Beware of using any adaptor for converting a 3 wire to 2 wire system
  4. Set up periodic checkout procedure to measure leakage current lvls on all electrical devices
  5. Hospitals n human subject labs should consider isolation of electrically sensitive areas
  6. Incorporate use of ground-fault circuit interruptors (perform like circuit breaker or fuse), and line unbalanced detectors in schools n homes
119
Q

What are general electrical safety rules

A
  1. When subject attached via recording electrodes to recording device, should b out of reach of electrically operated devices
  2. Equipment properly grounded
  3. Use only one hand when working with energize circuit
  4. Use back of hand to touch electrical equipment
120
Q

What kind of equipment should be taken out and serviced repaired

A
  1. Wet or subject to liquids

2. Dropped or abused or loose internal/external parts