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Step 1 Pharmacology > Reactions > Flashcards

Reactions Flashcards

1
Q

coronary vasospasm - 3

A

cocaine
sumatriptan
ergot alkaloids

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2
Q

cutaneous flushing - 4

A

VANC

vancomycin
adenosine
niacin
Ca channel blockers

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3
Q

dilated cardiomyopathy - 2

A

daunorubicin

doxorubicin

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4
Q

Torsades de pointes - 5

A 
III
Ia
macrolides
antipsychotics
TCAs
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5
Q

adrenocortical insufficiency - 1

A

glucocorticoid withdrawal —> HPA suppression

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6
Q

hot flashes - 2

A

tamoxifen

clomiphene

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7
Q

hyperglycemia - 6

A

Taking Pills Necessitates Having Blood Checked

Tacrolimus
Protease inhibitors
Niacin
HCTZ
B-blockers
corticosteroids
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8
Q

hypothyroidism - 3

A

lithium
amiodarone
sulfonamides

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9
Q

acute cholestatic hepatitis/jaundice - 1

A

erythromycin

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10
Q

diarrhea - 5

A

Might Excite Colon On Accident

Metformin
Erythromycin
Colchicine
Orlistat
Acarbose
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11
Q

focal to massive hepatic necrosis - 4

A

HAVAc

Halothane
Amanita phalloides
Valproic acid
Acetaminophen

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12
Q

hepatitis - 1

A

INH

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13
Q

pancreatitis - 6

A

Drugs Causing A Violent Abdominal Distress

Didanosine
Corticosteroids
Alcohol
Valproic acid
Azathioprine
Diuretics (loop and HCTZ)
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14
Q

pseudomembranous colitis - 3

A

clindamycin
ampicillin
cephalosporins

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15
Q

agranulocytosis - 6

A 
Clozapine
Carbamazepine
Colchicine
Dapsone
Methimazole
PTU
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16
Q

aplastic anemia - 6

A

Can’t Make New Blood Cells Properly

Carbamazepine
Methimazole
NSAIDs
Benzene
Chloramphenicol
PTU
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17
Q

Direct Coombs pos+ hemolytic anemia - 2

A

methyldopa

penicillin

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18
Q

gray baby syndrome - 1

A

chloremphenicol

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19
Q

hemolysis in G6PD deficiency - 7

A

IS D PAIN

INH
Sulfonamides
Dapsone
Primaquine
Aspirin
Ibuprofen
Nitrofurantoin
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20
Q

megaloblastic anemia - 3

A

Having a blast with PMS

Phenytoin
Methotrexate
Sulfa drugs

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21
Q

Thrombocytopenia - 2

A

heparin

cimetidine

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22
Q

Thrombotic complications - 1

A

OCPs

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23
Q

fat redistribution - 2

A

fat PiG

protease inhibitors
glucocorticoids

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24
Q

gingival hyperplasia - 4

A

phenytoin
verapamil
cyclosporin
nifedipine

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25
Q

hyperuricemia - 5

A

Painful Tophi and Feet Need Care

Pyrazinamide
Thiazides
Furosemide
Niacin
Cyclosporin
26
Q

myopathy - 8

A 
fibrates
niacin
colchicine
hydroxychloroquine
IFNa
penicillamine
statins
glucocorticoids
27
Q

osteoporosis - 2

A

corticosteroids

heparin

28
Q

photosensitivity - 4

A

SAT For a photo

sulfonamides
amiodarone
tetracyclines
5-FU

29
Q

stevens johnson syndrome - 4/8

A

Steven Johnson has EPILEPTIC ALLergy to sulfa drugs and penicillin

  • anti-EPILEPTICS (ethosuximide, carbamazapine, lamotrigine, phenytoin, phenobarbital)
  • ALLOPURINOL
  • SULFA DRUGS
  • PENICILLIN
30
Q

SLE-like syndrome - 6

A

SHIPP-E

sulfa drugs
hydralazine
INH
Procainamide
Phenytoin
Etanercept
31
Q

teeth discoloration - 1

A

tetracyclines

32
Q

tendonitis/tendon rupture/cartilage - 1

A

fluoroquinolones

33
Q

cinchonism - 2

A

quinidine, quinine

34
Q

parkinson-like syndrome - 3

A

ARM

antipsychotics
reserpine
metoclopramide

35
Q

seizures - 6

A

I BITE Myself

INH - B6 deficiency
Bupropion
Imipenim/cilastatin
Tramadol
Enflurane
Metoclopramide
36
Q

tardive dyskinesia - 2

A

antipsychotics

metoclopramide

37
Q

diabetes insipidus - 2

A

lithium

demeclocycline

38
Q

fanconi syndrome - 1

A

expired tetracycline

39
Q

hemorrhagic cystitis - 2

A

cyclophosphamide, ifosfamide

40
Q

interstitial nephritis - 3

A

methicillin
NSAIDs
furosemide

41
Q

SIADH - 4

A

Can’t Concentrate Serum Sodium

carbamazepine
cyclophosphamide
SSRIs

42
Q

dry cough - 1

A

ACE inhibitors

43
Q

pulmonary fibrosis - 4

A

Breathing Air Badly from Medication

Bleomycin
Amiodarone
Busulfan
Methotrexate

44
Q

antimuscarinic effects - 4

A

atropine
TCAs
H1 blockers
antipsychotics

45
Q

disulfaram like reaction - 5

A 
metronidazole
cephalosporins
griseofulvin
procarbazine
1st gen sulfonylureas
46
Q

CYP450 inducers

A

Corona, Miller, Sierra Nevada, Guinness, and PBR cause Chronic Alcoholism

Carbamazepine
Modenafil
St. John's Wort
Neviripine
Griseofulvin
Phenytoin
Barbiturates
Rifampin
Chronic alcohol
47
Q

CYP450 inhibitors - 13

A

CRAQCK AMIGGOS

cimetidine
ritonavir
acute alcohol
quinidine
ciprofloxacin
kenoconazole
amiodarone
macrolides
INH
gemfibrozil
grapefruit juice
omeprazole
sulfonamides
48
Q

sulfa drugs - 8

A

Popular FACTSSS

Probenecid
Furosemide
Acetazolamide
Celecoxib
Thiazides
Sulfonamide antibiotics
Sulfasalazine
Sulfonylureas
49
Q

macrolides cause - 2

A
  • torsade de pointes

- CYP450 inhibitor

50
Q

protease inhibitors cause -

A
  • hyperglycemia

- fat redistribution

51
Q

nephrotoxicity - 4

A

aminoglycosides
vancomycin
loop diuretics
cisplatin

52
Q

niacin causes - 4

A
  • cutaneous flushing
  • hyperglycemia
  • hyperuricemia
  • myopathy
53
Q

isoniazid (INH) causes - 5

A
  • hepatitis
  • hemolysis in G6PD deficiency
  • SLE-like syndrome
  • seizures
  • CYP450 inhibitor
54
Q

HCTZ/thiazides cause - 3

A
  • hyperglycemia
  • pancreatitis
  • hyperuricemia
55
Q

TCAs cause - 2

A
  • torsades de pointes

- anti-muscarinic effects

56
Q

tetracyclines cause - 3

A
  • photosensitivity
  • teeth discoloration
  • fanconi syndrome (expired)
57
Q

sulfa drugs cause - 7

A
  • hypothyroidism
  • megaloblastic anemia
  • hyperuricemia
  • hemolysis in G6PD deficiency
  • stevens-johnson syndrome
  • pancreatitis
  • disulfaram like reaction
  • CYP450 inhibition
58
Q

phenytoin causes - 5

A
  • stevens-johnson syndrome
  • SLE-like syndrome
  • megaloblastic anemia
  • gingival hyperplasia
  • CYP450 inducer
59
Q

amiodarone causes - 4

A
  • hypothyroidism
  • photosensitivity
  • pulmonary fibrosis
  • CYP450 inhibitor
60
Q

methotrexate causes - 2

A
  • megaloblastic anemia

- pulmonary fibrosis

61
Q

antipsychotics cause -

A
  • torsade de pointes
  • parkinson like syndrome
  • tardive dyskinesia
  • antimuscarinic effects

Step 1 Pharmacology (7 decks)

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