RBCs and Anemias lecture

Question 1

Where does erythropoiesis occur

Answer 1

Bone marrow

Question 2

Where is erythropoietin produced

Answer 2

kidneys

Question 3

What is a reticulocyte

Answer 3

an immature RBC

Question 4

What is the lifetime of a RBC

Answer 4

120 days

Question 5

What are the 3 general classifications of anemia

Answer 5

Decreased RBC PRODUCTION(reticulocytopenia), DESTRUCTION(reticulocytosis) , or BLOOD LOSS

Question 6

What are the general normal reference ranges for anemia

Answer 6

Females: Hgb <12 g/dL
Males: Hgb <14 g/dL

Question 7

You have a young child come to you with exhaustion and craving for specific foods like ice, dirt, and paper. What other symptoms would you expect them to have and what disorder are you thinking about?

Answer 7

Think about Iron deficiency anemia (IDA)
Have PICA (craving for ice or dirt), brittle nails, dysphagia due to esophageal webs.
PE will show smooth tongue (atrophic glossitis, angular cheilosis/chelitis, Spoon nails (Koilonychia).

Question 8

You have a young child come to you with anemia symptoms and dysphagia. What other symptoms would you expect them to have and what disorder are you thinking about?

Answer 8

Think about Iron deficiency anemia (IDA)
Have PICA (craving for ice or dirt), brittle nails, dysphagia due to esophageal webs.
PE will show smooth tongue (atrophic glossitis, angular cheilosis/chelitis, Spoon nails (Koilonychia).

Question 9

If you see Koilonychia and angular chelitis, what might the patient have?

Answer 9

Iron deficiency anemia

Question 10

Your patient has low Hgb, Low MCV, Low MCH, Low Retic, Low ferritin, Low serum iron, and Elevated TIBC. What might be going on? What symptoms might they have?

Answer 10

Iron deficiency anemia.

Have PICA (craving for ice or dirt), brittle nails, dysphagia due to esophageal webs.
PE will show smooth tongue (atrophic glossitis, angular cheilosis/chelitis, Spoon nails (Koilonychia).

Question 11

Most common cause of reticulocytopenia

Answer 11

Iron deficiency

Question 12

You have a patient who has a priapism. What disease is this characteristic of

Answer 12

Sickle cell crisis

Question 13

You have a patient who has dactylitis. What disease is this characteristic of

Answer 13

Sickle cell disease ( Infarction of bone/pain crisis occuring in hands)

Question 14

Your pathology report shows a patient has Howell-Jolly bodies on a blood smear. What is this characteristic of

Answer 14

Sickle Cell disease