Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Hematology > rbc disorders > Flashcards

rbc disorders Flashcards

1
Q

what are the INSUFFICIENT erythropoiesis

a. ida
b. sarcoidosis
c. sideroblastic anemia
d. anemie due to renal disease

A

in S ufficient erythropoiesis
> ISA3<

I - IDA
S- SARCOIDOSIS
A
   - ANEMIA DUE TO RENAL DISEASE
  - ACUTE LEUKEMIA
  - APLASTIC ANEMIA
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

INEFFECTIVE ERYTHROPOIESIS, EXCEPT:

a. megaloblastic anemia
b. thalassemia
c. sarcoidosis
d. myelopthsic syndrome

A

ineffective erythopoiesis
> mt sm<

m- megaloblastic anemia
t- thalassemia
s- SIDEROBLASTIC ANEMIA
m - myelopthsic syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what are the initial lab test to be done in diagnosing anemia

a. cbc
b. reticulocyte
c. bone marrow
d. pbs

A

initial test for diagnosing anemia

cbc
reticulocytes
pbs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what are the three major pathophysiological cause of anemia

a. blood loss, insuficient erythropoiesis, acanthocytes
b. blood loss, impaired red blood cell production, accelerated red cell destruction
c. blood loss, impaired rbc production

A

three pathophysiological cause of anemia

> BIA<
b - BLOOD LOSS

I - INPAIRED RED BLOOD CELL PRODUCTION

A - ACCELERATED RED CELL DESTRUCTION

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

anemia caused by DECREASED PRODUCTION OF RBCs

a. insufficient and ineffective erythropoiesis
b. bone marrow failure and impairement of erythroid development
c. intrinsic rbc abnormlaity, extrinsic rbc abnormality and blood loss

A

Anemia cause by DECREASED PRODUCTION of RBCs

  1. Bone Marrow Failure
  2. impairement of erythroid development
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

bone marrow failure, except:

a. myelopthsic anemia
b. megaloblastic anemia
c. aplastic anemia
d. pure red cell aplasia

A

ans: MEGALOBLASTIC ANMEIA

bone marrow failure
>MAP<

M - MYELOPTHSIC ANEMIA
A - acquired and congenital APLASTIC ANEMIA
P- PURE RED CELL APLASIA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

its is impairment of erythroid development that is due to hemoglobin synthesis

a. megaloblastic anemia
b. thalassemia
c. anemia due to renal disease

A

ans: thalassemia

mpairment of erythroid development:
- due to Hemoglobin synthesis

> H(gb)ITS Aci

I - IDA
T- THALASSEMIA
S- SIDEROBLASTIC ANEMIA
Aci - ACUTE CHRONIC INFAMMATION

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

its is impairment of erythroid development that is due to hemoglobin synthesis

a. sideroblastic anemia
b. anemia due renal disease
c. megaloblastic anemia

A

impairment of erythroid development:
- due to Hemoglobin synthesis

> H(gb)ITS Aci

I - IDA
T- THALASSEMIA
S- SIDEROBLASTIC ANEMIA
Aci - ACUTE CHRONIC INFAMMATION

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

impairment of erythroid development that is due to DNA synthesis

a, thalassemia

b. sideroblastic anemia
c. megaloblastic anemia

A

due to DNA synthesis

- megaloblastic anemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

impairment of erythroid development due to production of epo

a, thalassemia

b. sideroblastic anemia
c. anemia caused by renal disease

A

decreased due to the production of EPO

- anemia caused by renal disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

increased rbc loss:
which of the following is not intrinsic membrane defect:

a. sideroblastic spherocytosis
b. sideroblastic elliptocytosis
c. paroxysmal cold hemoglobinuria
d. paroxysmal nocturnal hemoglobinuria

A

ans: paroxysmal COLD hemalobinuria

intrinsic rbc abnormality : MEMBRANE DEFECT

a. sideroblastic spherocytosis
b. sideroblastic elliptocytosis / Pyropoikilocytosis
d. paroxysmal nocturnal hemoglobinuria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

intrinsic rbc abnormality

a. membrane and enzymatic defect
b. immune and non immune
c. blood loss

A

intrinsic rbc abnormality : membrane and enzyme defect

extrinsic rbc abnormality : immune and non immune causes

blood loss : acute and chronic blood loss anemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

increased rbc loss:
what are the extrinsic abnormality : immune defect

a. paroxysmal cold hemaglobinuria
b. paroxysmal nocturnal hemaglobinuria
c. htr
d. hdn
e. warm type autoimmune hemolytic anemia

A

extrinsic rbc abnormality : immune causes:

  1. warm type autoimmune hemolytic anemia
  2. cold agglutinin disease
  3. paroxysmal COLD hemaglobinuria
  4. htr
  5. hdn
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

extrinsic rbc abnormality

microangiopathic hemolytic anemia (TTP, HUS, HELLP, DIC)

a. immune cause
b. non immune cause

A

non immune cause

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

alcoholism

a. microcytic
b. normocytic
c. macrocytic

A

macrocytic - non megaloblastic anemia —–>

chronic LIVER DISEASE]
ALCOHOLISM
APLASTIC ANEMIA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

HBE DISEASE

a. microcytic
b. normocytic
c. macrocytic

A

microcytic —- TAILS CHe

T  - THALASSEMIA
A  - ANEMIA OF CHRONIC INFAMMATION
I   -  IDA
L - LEAD POISONING
S - SIDEROBLASTIC ANEMIA

C -CHRONIC BLOOD LOSS
He - HEMOGLOBIN E DISEASE

17
Q

after MCV then the result is normal what test to be next?

a. iron studies
b. reticulocytes
c. pbs

A

reticulocytes

iron studies is for MICROCYTIC

18
Q

MYELODysPLASIA

A. microcytic

b. normocytic
c. macroytoc

A

macrocytic - megaloblastic —–

vitamin b12 deficiency
folate deficiency
myelodysplasia
erytholeukemia
some drugs
19
Q

most common form of anemia

a. iron deficiency anemia
b. anemia of chronic infammation
c. anemia due to lead poisoning

A

iron deficiency anemia

20
Q

iron compartments in normal human
which of the following are the storage compartment

a. ferritin
b. myoglobin
c. transferrin

A

FUNCTIONAL compartment

  1. myoglobin
  2. hemoglobin
  3. peroxidase , catalase, cytochromes, riboflavin

STORAGE compartment IRON

  1. ferritin
  2. hemosiderin

TRANSPORT
1. transferrin

21
Q

decreased: hgb , serum iron, tibc, ferritin

a. storage depletion
b. transport depletion
c. functional depletion

A

FUNCTIONAL DEPLETION : decreased: hgb , serum iron, tibc, ferritin

22
Q

NORMAL : hgb , serum iron, tibc,
DECREASED : ferritin

a. storage depletion
b. transport depletion
c. functional depletion

A

STORAGE DEPLETION
NORMAL : hgb. serum iron, tibc

decreased ; ferritin

23
Q

it is microcytic , hypochromic anemia due to inability to use available iron for hgb production

a. ida
b. aci
c. sideroblastic anemia

A

anemia of chronic inflammation

24
Q

it is a microcytic , hypochromic anemia that is caused by blocks in the protoporphyrin pathway resulting in defective hgb synthesis and iron overload

a. ida
b. aci
c. sideroblastic anemia

A

sideroblastic anemia - may nag block kaya di lumalabas yung iron/ may pumipigil

25
Q

excess iron accumulates in the mitochondrial region of the immature rbc in the bm and encircles the nucleus; cells are called

a. ringed sideroblasts
b. ringed siderocytes
b. ringed spherocytes

A

ringed sideroblasta – immature rbc

ringed siderocytes —- MATURE RBC

26
Q

what enzyme does anemia due to lead poisoning inhibits?

a. pyruvate kinase
b. g6pd
c. ferrochelatase

A

ferrochelatase and d - ala synthase enzyme in heme/ protoporphyrin pathway

27
Q

chronic exposure to lead what anemia can be seen?

a. normocytic and normochromic
b. microcytic and hypochromic

A

anemia, when present exposure to lead – normo, normo ,, HOWEVER, WITH CHRONIC EXPOSURE ITS MICROCYTIC AND HYPOCHROMIC

Hematology (10 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions