rats and mice ap Flashcards

1
Q

rats and mice have tails that are longer than their body length (T/F)

A

true

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2
Q

rats have a gallbladder (T/F)

A

false

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3
Q

the inguinal canal in males remains open throughout life (T/F)

A

true

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4
Q

mice and rats typically breed during daylight hours (T/F)

A

false

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5
Q

secretions from the harderian gland in rats is commonly called _____

A

red tears

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6
Q

brown fat, commonly called _____ is located around the ____, and ____. it provides roughly __ times the energy storage as other fats

A

hibernation tissue, neck, scapulae, 10

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7
Q

gestation for mice is _____ days and ____ days for rats

A

19-21, 21-23

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8
Q

mice reach puberty at __ weeks and rats at ____ weeks

A

5, 5-9

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9
Q

the average lifespan of mice is ____ and ___ for rats

A

1-3, 2-3

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10
Q

the normal TPR for mice

A

T - 98.6, P - 427 - 697, R - 91 - 146

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11
Q

the normal TPR for rats

A

T - 98.6, P - 313 - 493, R - 71 - 146

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12
Q

rats and mice have __ digits on the forelimbs, and ___ digits on the hindlimbs

A

4,5

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13
Q

female rats have ___ pairs of mammary glands, they are found in the ____ and ___ areas

A

4-6, thoracic, inguinal

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14
Q

female mice have ___ pairs of mammary glands, they extend to the ___ and ____

A

5, sides and back

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15
Q

male mice also have mammary glands but their nipples are

A

insignificant

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16
Q

the uterus of mice and rats is considered to be ____ and each uterine horn has a separate ______

A

bicornuate, cervical canal

17
Q

female mice and rats are ______ ovulators, and they are considered ______ with their estrous period lasting ____ days

A

spontaneous, continuously polyestrous, 4-5 days

18
Q

in mice and rats the postpartum estrus occurs roughly ___ hours after parturition

A

20-24

19
Q

the presence of a copulatory plug can be used to confirm _____

A

breeding

20
Q

mice and rats have ____ teeth

A

hypsodont

21
Q

___ animals are the direct result of mating between two different inbred strains

A

hybrid

22
Q

_____ strains develop as a result of genetic mutation in existing strains. the mutation is then carried on in future generations

A

coisogenic

23
Q

___ strains are those in which a mutation that arises in one strain is transferred to another strain through a series of backcross mating. nude animals were developed

A

congenic

24
Q

a ___ is a mouse whose DNA has been modified so that it does not express particular proteins

A

knockout mouse

25
Q

why cant rats vomit

A

the limiting ridge separates the 2 portions of the stomach, covers the opening from the esophagus

26
Q

unique structure of the rats lungs

A

divided unequally, left lobe is smaller and single, the right lobe is larger and divided into 4 sections

27
Q

what is a copulatory plug and how long does it remain in place

A

when dried semen mixes with secretions from the vagina, 12-24 hours after mating

28
Q

chromodacryorrhea is

A

normal red secretions of the eyes, commonly occurs when the animal is stressed

29
Q

purpose of tails

A

organ of balance and helps with heat loss

30
Q

rats pancreas

A

highly diffuse, located throughout the mesentery, many ducts that supple digestive enzymes to the small intestine

31
Q

what is an intensive breeding program for mice and rats

A

continuous housing of male and female animals

32
Q

what is a non intensive breeding program

A

separate housing for the males and females while pregnant

33
Q

what is the bruce effect

A

when a prego mouse is exposed to a new male (odor) within 4 days of breeding, the existing pregnancy will be aborted and female returns to estrus

34
Q

what is the whitten effect

A

when females are exposed to a male / odor, they will begin estrus within 3 days

35
Q

what is a stock bred animal

A

a mouse/rat that has been randomly bred

36
Q

when is an inbred animal considered a strain

A

when atleast 20 gens of parent offspring matings have occured

37
Q

5 ways to ensure genetic purity

A

protein electrophoresis, serologic testing, mandible measurements, backcross mating, tissue transplants

38
Q

what is a transgenic animal

A

an animal who has had some DNA removed from one strain and is inserted into an ovum after fertilization

39
Q

why do we use mice and rats in research

A

they have a well characterized genetic makeup, and can be bred to be specifically susceptible to certain diseases