Chapter 1 and 3 Flashcards
research directed toward specific objectives, such as development of new drugs is referred to as _____
applied research
the use of computer models or plants in research is an example of
basic research
dvms who have reached the highest degree of proficiency in lab animal medicine are board certified by
ACLAM
the organization that determines the criteria for certification for ALAT, LAT, LATG
AALAS
the level of certification that requires the miniumum of GED or high school diploma and at least 3 years of experience is the
LAT
thermoneutral zone
the rang of temp where an animal has no physical or mechanisms needed to control heat loss / production
a biomedical facility designed for housing of germ free animals is referred to as a ___ facility
barrier
what is a microenvironment
temp, humidity, lighting, and ventilation within the primary enclosure of animals
animal rooms must have a minimum of ____ room air changes per hour
10-15
which type of room should be under negative air pressure
quarantine
a diurnal lighting system is one that uses ___ hours of light followed by ___ hours of darkness
12, 12
a type of plastic used for cages that is transparent and has high impact strength and resistance to high heat and chemicals is ____
polycarbonate
the study of animals with completely known flora and fauna is referred to as
gnotobiology
animals that are known to be free of certain pathogens are referred to as _______
specific pathogen free
animals kept in animal rooms and experimental areas that undergo periodic testing to identify the presence of any microorganisms in the animal colonies are reffered to as
sentinel animals
ALAT
assistant lab animal technician
LAT
laboratory animal technician
LATG
lab animal technologist
the term ___ generally refers to any companion animals other than dogs or cats
exotic pet
any animal used in research or teaching is referred to as a
lab animal
nearly all medications using in exotic and lab animal medicine are considered
extra label use
predisposing factors such a sp, age, gender, and heredity are considered ____ factors
intrinsic
_____ is the organization that was formed to safeguard sp from extinction
CITES
the government agency that oversees the use of animals in an educational or research institution is the
USDA
the ____ is the principle federal statute governing the sale, handling, transport, and use of animals
animal welfare act
the guide for the care and use of lab animals was written under the directions of the ___
ILAR
the ___ oversees the institutional investigations into research misconduct and promotes the responsible conduct of research through the educational, preventative, regulatory activities
ORI
____ refers to research that utilizes lower forms of life, computer models or other artificial means whenever possible
replacement
___ and ___ are the most commonly used lab animals
mice and rate
species that are excluded from the AWA regulations are covered by the regulations contained in ______
the guide
the AWA set standards of care for lab animals and is implemented through
AWR / USDA
the institutional group charged with evaluation of animal use and inspection of facilities is
IACUC
the group that provides voluntary accreditation or biochemical research facilities is _____
AAALAC
____ are the main benefit of animal research
medical advances
it currently takes about ____ years of lab studies, along with animal and human clinical trials, before a medication can be released for human use
10-12
prions were discovered and characterized in what year
1997
the use of procedures that causes the least amount of stress, pain, anxiety and disturbance of normal life the animal is an example of
refinement
thanks to research the vaccine for rabies was discovered in ___ thanks to teh ___ and ___
1885, dog and rabbit
the 2 most active animal liberation groups in the US
PETA and ALF
specific environmental parameters such as temp, humidity, lighting, noise, and ventilation are considered ___ factors
extrinsic
most medications used in exotic animal medicine must be _____
diluted
the minimum membership of IACUC
minimum of 3 members, 1 DVM w training, ! with no affiliation to the facility, and a nonscientist
Reduction
using the least number of animals
refinement
least amount of stress, anxiety, pain, or disturbance
replacement
utilize lower forms of life
the AWA was originally titled the lab animal welfare act - 3 purposes
protect owners, prevent sale of stolen animals, insure animals intended for use in research provided w humane care and tx
9 standards in the guide
qualifications and credentials of personnel, OSH, veterinary care, animal envrionment, animal procurement and transportation, surgery and post care, pain relief, euthanasia technique, physical plant design
owners of exotic pets must ensure what 3 factors are properly addressed
husbandry, welfare, safety
IACUC
institutional animal care and use committee
FDA
food and drug administration
AAALAC
association for assessment and accreditation of lab animal care
SOPs
standard operating procedures
GLP
good lab practice
PETA
people for the ethical treatment of animals
ALF
animal liberation front
OLAW
office of lab animal welfare
PHS
public heath service
AWA
animal welfare act
APHIS
animal and plant health inspection service
ILAR
institute for lab animal research
REAC
regulatory enforcement and animal care
EPA
environmental protection agency
NIH
national institute of health
